desmoid tumor
Introduction
Introduction to hard fibroma Hard fibroma, also known as ligament-like tumor, is a rare form of benign hypertrophy of the benign diaphragm. It is estimated that 3.7 new cases occur in a million population each year. It occurs in muscles, aponeurosis and deep fascia, and is very hard. The disease can occur throughout the body, more common in the abdominal wall, but also in the abdomen and skeletal muscle. Hard fibroma occurs mostly in the 30 to 50 years old and is more common in women. Also seen in teenagers. basic knowledge Sickness ratio: 0.05% Susceptible people: Most occur in 30 to 50 years old, more common in women. Also seen in teenagers. Mode of infection: non-infectious Complications: traumatic ulcer
Cause
Cause of dural fibroma
Genetic factors (50%):
The etiology of this disease is unknown, may be related to surgery and systemic connective tissue abnormalities, elevated estrogen in the blood during pregnancy, and may cause abdominal wall damage during the production process, which may be the cause of hard-oncoma in adult women, hard Fibroids can also be used as part of the Gardner syndrome consisting of multiple polyps of the rectum, osteoma, skin cysts and hard fibroids, the latter having a genetic family history.
Prevention
Hard fibroma prevention
It is mainly aimed at preventing various factors that may cause skin fibroids. It is currently believed that the loss of normal immune surveillance function, the tumorigenic effect of immunosuppressants, the activity of latent viruses and the long-term application of certain physical (such as radiation), chemical (such as anti-epileptic drugs, adrenocortical hormone) substances, Lead to the proliferation of lymphatic network, and eventually skin fibroids. Therefore, pay attention to personal and environmental hygiene, avoid drug abuse, and pay attention to personal protection when working in a harmful environment.
Complication
Hard fibroma complications Complications, traumatic ulcers
Complications of cutaneous fibroids: ulceration can occur in skin fibroids after trauma. The clinical signs of cutaneous fibroids are solid and hard to touch. They are attached to the epidermis and do not adhere to the deep tissues. The lower part can move freely. At the side pressure, the center of the nodule is characterized by tiny dimples, and the "dimple" sign is positive. (The thumb and the index finger are used to pinch the tumor from both sides, and the skin above it is slightly depressed.
Symptom
Symptoms of hard fibroids Common symptoms Slow growth Abdominal tenderness Upper abdominal mass and bloating
Occurred in the abdominal wall, showing a painless abdominal wall mass, hard, no tenderness, slow growth, most patients can be found when the tumor diameter is several centimeters, a few delay treatment, the tumor is flaky infiltration around the tumor, Causes a large abdominal wall stiffness, which occurs in other parts, can cause corresponding compression symptoms and dysfunction.
1. More common in the gestational period or through the maternal abdominal wall muscles, can also occur in other areas of the striated muscle.
2. The lump grows slowly, is painless, hard and has unclear boundaries with surrounding tissues.
Examine
Hard fiber tumor examination
Histopathological examination showed that the cut surface was grayish, yellowish brown or dark brown, and the lower boundary was clear. There was often a "boundary zone" composed of immature collagen fibers between the upper boundary and the epidermis. The lesions are mainly located in the dermis. Microscopically, fibroblasts, histiocytes, endothelial cells and mature or naive collagen fibers are observed. The central epidermis of the lesions is obviously hyperplasia, the acanthosis is hypertrophy, and the skin processes are prolonged. It can be divided into two types: fibrous damage and cell type damage. The former consists of scattered immature collagen fibers, light blue, irregularly arranged into interlaced and anastomotic strips, which are spiral or wheel-shaped, with narrow nuclei between fibers. Fibroblasts. The latter consists of a large number of fibroblasts and a small amount of collagen fibers. Many cells have large, round or oval nucleus, are rich in chromatin, rich in cytoplasm, and may contain lipids in the cells or contain hemosiderin. . Sometimes cells can be atypical.
Diagnosis
Diagnosis and diagnosis of hard fibroma
Clinically, it should be differentiated from cutaneous cutaneous sarcoma and nodular pruritus.
1. Protuberance cutaneous fibrosarcoma: many cellular components. The nucleus is large and has a slight profile, with more divisions. Progressive enlargement, the diameter of more than 2 ~ 3cm suggests malignant fibrous histiocytoma, or hyperplastic cutaneous sarcoma, should be removed biopsy.
2. Nodular pruritus: occurs in the extremities of the extremities, multiple hairs and the same size, will not increase to a large extent, itching is obvious without tingling, often associated with insect bites, histopathology is epidermal or papillary hyperplasia There is no proliferation of collagen fibers and tissue cells in the dermis.
