Fibrocartilaginous stromal tumor
Introduction
Introduction to fibrocartilage stromal tumor Fibrocartilage stromal tumors are composed of two different tissues, one is cartilage-like tissue, which is benign, similar to the growing tarsal plate; the other is similar to low-grade fibrosarcoma, which is rare. Occurs in men, ages 9 to 23 (average 13 years). Occurs in men, ages 9 to 23 (average 13 years). Located at the metaphysis of the proximal end of the humerus, it only affects the genus in adulthood. Tumors grow slowly, may have mild discomfort, tenderness, such as in the superficial bone, visible regular, hard bone swelling, clear boundaries. basic knowledge Sickness ratio: 0.0001% Susceptible people: good for men Mode of infection: non-infectious Complications: chondrosarcoma multiple myeloma
Cause
Fibrocartilage stromal tumor etiology
The cause of this disease is unknown, and it is speculated that it may be related to environmental, genetic, trauma, and nutrition.
Pathological change
1. Visible to the naked eye: the tumor is hard, white, bundle-like appearance, similar to hard fibroids or low-grade fibroid sarcoma. In the matrix, cartilage-like substances have a special spiral shape, which resembles a growing cartilage plate.
2. Seen under the microscope: there are continuous, intersecting spindle cells and collagen fiber bundles. In the tumor tissue, the nucleus is full, pleomorphic and stained too deeply, and mitosis is rare. There are well-defined cartilage islands in the matrix. These cartilage are well differentiated and benign. They often form a thick wavy band, similar to the tarsal plate, with progressive columnar, hyperplastic and endochondral ossification. In short, the main component of fibrocartilage stromal tumors is similar to grade I fibrosarcoma, and another distinct component is similar to the tarsal plate, suggesting a benign, organoid, and hamartoma.
Prevention
Fibrocartilage stromal tumor prevention
The disease is slow, but the low-grade malignant tumor often recurs after the lesion is resected, and even relapses after a few years after surgery. The primary tumor and the recurrent tumor should be resected with tumor, no metastasis report. .
Complication
Fibrocartilage stromal tumor complications Complications chondrosarcoma multiple myeloma
Can be complicated by infection, chondrosarcoma, myeloma and other diseases.
Symptom
Fibrocartilage stromal tumor symptoms Common symptoms Muscle tenderness Endochondral ossification slow growth
Occurs in men, ages 9 to 23 (average 13 years). Located at the metaphysis of the proximal end of the humerus, it only affects the genus in adulthood. Tumors grow slowly, may have mild discomfort, tenderness, such as in the superficial bone, visible regular, hard bone swelling, clear boundaries.
Examine
Fibrocartilage stromal tumor examination
Seen on the X-ray:
It is a transparent lesion adjacent to the growth tarsal plate. In adults, it can invade the sacral end. The contour of the bone is moderately dilated. The cortical bone is thinner and can be scalloped or lobulated. The cortical bone often has a small destruction zone. Out, invasive soft tissue, periosteal reaction is rare, and it shows chronic reaction. Therefore, the surface of thin cortical bone is smooth or slightly rough. There are often some inorganic salt deposits in the tumor, such as granular or ring-shaped, suggesting cartilage. Ingredients; if it is a mist, it suggests a bone component.
Diagnosis
Diagnosis and diagnosis of fibrocartilage stromal tumor
In imaging, several tumors need to be identified, non-ossogenic fibroma and low-grade malignant fibrosarcoma tumors without mineral deposits; chondrosarcoma does not occur in juvenile patients; chondroblastoma is frosted glass or cloud-like density Increased shadow, not granular, ring; giant cell tumor of bone is rare in the growing season, no mineral-free deposition; childhood osteosarcoma and adult clear cell chondrosarcoma need to be identified, histological needs The fiber structure is poorly identified, and the fibrous structure is poor, and the fibrous tissue component is benign. In addition, the fibrous structure is poor, and the bone island is not similar to the growth cartilage.
