Leiomyosarcoma
Introduction
Introduction to smooth osteosarcoma Smooth osteosarcoma occurs in 40 to 60 years old and occurs in the extremities. It usually has a long course of disease. It is easy to relapse after local excision. It can be transferred to the lungs, liver and other organs by blood. A few metastasize to local lymph nodes. The softness of pediatric soft tissue leiomyosarcoma Low, the prognosis is better. According to the different parts, there are three types: 1 skin, subcutaneous type. 2 posterior peritoneum, mesenteric type. 3 vascular type. Smooth osteosarcoma is the same as other human tumors. The cause is unclear and the mechanism is unknown. The pathogenesis factors are very complicated. The internal factors include quality theory, genetic theory, endocrine theory, etc.; external factors include chemical substances and internal and external irradiation, chronic inflammation stimulation theory, and viral infection theory. Wait. Other benign bone tumors such as Paget's disease, giant cell tumor of bone and poor structure of bone fibrous tissue may be secondary to osteosarcoma, which is more common in patients after middle age. basic knowledge The proportion of illness: 0.0002% Susceptible people: more common in 40 to 60 years old Mode of infection: non-infectious Complications: anemia, multiple system organ failure
Cause
Smooth osteosarcoma etiology
Cause:
Smooth osteosarcoma is the same as other human tumors. The cause is unclear and the mechanism is unknown. The pathogenesis factors are very complicated. The internal factors include quality theory, genetic theory, endocrine theory, etc.; external factors include chemical substances and internal and external irradiation, chronic inflammation stimulation theory, and viral infection theory. Wait. Other benign bone tumors such as Paget's disease, giant cell tumor of bone and poor structure of bone fibrous tissue may be secondary to osteosarcoma, which is more common in patients after middle age.
Prevention
Smooth osteosarcoma prevention
The focus of prevention is the spread of cancer-related medical knowledge, which has led to increased awareness and understanding of osteosarcoma and increased vigilance. Health conditions and improved quality of health care are the guarantees of early detection. Pain in the proximal joints with no history of trauma, especially in adolescents, should be treated as soon as possible to exclude osteosarcoma. The disease may be related to some external stimuli, such as X-rays, etc., should avoid contact and attention to protection. Some benign lesions can also be converted into osteosarcoma, such as osteochondroma, giant cell tumor, bone fiber dysplasia, etc., patients with these diseases should be reviewed regularly according to the doctor's advice.
Complication
Smooth osteosarcoma complications Complications, anemia, multiple system organ failure
It can be transferred to the lungs, liver and other organs through the blood, and a few are transferred to the local lymph nodes. In the early stage, the general condition was good, and symptoms such as fever, weight loss, and anemia appeared in the late stage of the disease, and eventually organ failure and cachexia were observed. Metastatic symptoms: Most patients with osteosarcoma develop symptoms of pulmonary metastases within one year. Initially, the lungs can be asymptomatic, and patients with advanced hemoptysis, belching, and difficulty breathing. Almost all metastases are transferred to the lungs via the blood, and a small number of metastases to the internal organs such as the brain and kidneys and lymph node metastasis cause corresponding symptoms.
Symptom
Smooth osteosarcoma symptoms Common symptoms Wrist pain and palm flexion... Long bone swelling, pain, bone pain
More common in 40 to 60 years old, occurs in the extremities, generally a longer course of disease, easy to relapse after local resection, can be transferred to the lungs, liver and other organs by blood, a small number of metastasis to local lymph nodes, pediatric soft tissue leiomyosarcoma with low malignancy, prognosis it is good.
Examine
Smooth osteosarcoma examination
X-ray examination: single hair, bone protrusion from the cortex to soft tissue at the metaphysis, the cortex and cancellous bone are connected to the normal bone with a narrow or wide pedicle, and the medullary cavity communicates with each other. , not developed, different thickness, sometimes can be irregular calcification.
Microscopic examination: The tumor cells are long fusiform in size. The ends of the nucleus are obtuse, the size is different, the cytoplasm is pink, and there are unequal longitudinal myofibrils.
Diagnosis
Diagnosis and diagnosis of smooth osteosarcoma
The problem of benign and malignant smooth muscle tumors is different. In a few cases, there are still difficulties. From the clinical point of view, the diameter of leiomyomas is more than 2.5cm, which is benign. Those above 2.5cm may be benign, deep and invade muscles and fascia. It is malignant. The main differential diagnosis is: ossifying myositis, bone tuberculosis, acute and chronic osteomyelitis, bone cyst and giant cell tumor of bone.
