benign fibrous histiocytoma
Introduction
Introduction to benign fibrous histiocytoma Benign fibrous histiocytoma is a benign tumor that originates in tissue cells and resembles histiocytic fibroids and giant cell tumors of bone. The periosteum and adjacent cortical connective tissue were normal to the naked eye, and the cortical bone was thin but continuous. The tumor is dense and consists of a jelly-like substance or a small amount of fibrous material, which is leather-like yellow and sometimes has bright yellow spots. There may be soft tissue next to the tissue, light brown or reddish brown, like giant cell tumor of bone, and the tumor and surrounding bone boundary are clear. The etiology of this disease is not clear, and may have certain correlation with environmental factors, genetic factors, dietary factors, and mood and nutrition during pregnancy. It may also be related to trauma. Seen under the microscope: the cells are rich, and the collagen is arranged in a spiral or laminar shape. The cells have a round-ellipse nucleus that elongates in the direction of the fiber. basic knowledge The proportion of illness: 0.005% Susceptible people: no specific population Mode of infection: non-infectious Complications: fracture
Cause
The cause of benign fibrous histiocytoma
The etiology of this disease is not clear, and may have certain correlation with environmental factors, genetic factors, dietary factors, and mood and nutrition during pregnancy. It may also be related to trauma. Seen under the microscope: the cells are rich, and the collagen is arranged in a spiral or laminar shape. The cells have a round-ellipse nucleus that elongates in the direction of the fiber. There are abundant large foam cells that can be isolated or in groups. Multinucleated giant cells are rare and small, and mitosis is rare.
Prevention
Benign fibrous histiocytoma prevention
Pay attention to safety in work and life, try not to deal with injuries or injuries, and treat them in a regular hospital to reduce the symptoms and complications. It is an effective preventive measure.
Complication
Benign fibrous histiocytoma complications Complications
There are no special complications, but because the bone cells are destroyed, it can cause the brittleness of the bones to increase, and even the rational fractures should be paid attention to in clinical practice. Because of the bone damage in this disease, when the bone cortex is destroyed, the patient will feel obvious pain, and the pain can affect sleep and emotional depression. However, the disease is a benign feature and complications are rare.
Symptom
Benign fibrous histiocytoma symptoms Common symptoms Soft tissue swelling hypertrophic nodular fibroplasia tissue cell proliferation
The incidence is rare, so far, only a few cases have been reported, so it is difficult to make accurate gender, age and location statistics. The disease is usually caused by adult disease, which occurs in the metaphysis of long bones, also in the humerus, humerus and jaw. Bone, the symptoms are persistent moderate pain and swelling.
Examine
Examination of benign fibrous histiocytoma
Seen on the X-ray
For osteolytic lesions, located at the metaphysis of the long bone, it is characterized by circular eccentricity, sometimes separated by a thin line of hardening of the bone to make the boundary clear, the cortical bone is thin, sometimes mildly swelled, in the smaller bone, such as the tibia. The head can occupy the entire bone segment, and sometimes part of the cortical bone can disappear, but no periosteal reaction.
Seen by the naked eye
Periosteum and adjacent connective tissue are normal. The cortical bone is thin but continuous. The tumor is dense. It consists of jelly-like substances or a small amount of fibrous substances. It is leather-like yellow and sometimes has bright yellow spots. It can be soft next to this tissue. Tissue, light brown or reddish brown, giant cell tumor like bone, clear tumor and surrounding bone boundary.
Seen under the microscope
The cells are abundant, and the collagen is arranged in a spiral or lamellar arrangement. The cells have a round-ovate nucleus, which can be elongated in the direction of the fiber. There are abundant large foam cells, which can exist in isolation or in groups. The multinucleated giant cells are rare and small. Mitotic images are rare, and structures similar to giant cell tumors of bone can be observed in certain areas (the gross pathological giant cell tumor area).
Diagnosis
Diagnosis and diagnosis of benign fibrous histiocytoma
It needs to be differentiated from non-ossifying fibroma and giant cell tumor of bone. Giant cell tumor of bone is a benign lesion of the bone, usually single and locally invasive. It is also believed that giant cell tumor of bone is a potentially malignant tumor. This tumor is neither completely benign nor completely malignant, but it is between these two extremes, and its degree of invasion is different. Some giant cell tumors can obtain long-term control after relatively simple surgery, and some Giant cell tumors can be spread and metastasized. X-ray examination shows a soapy appearance.
