fibroblastoma

Introduction

Introduction to fibrillar fibroma Fibrofibromas are mature fibroids, like soft tissue fibroids, and are as prone to recurrence as they are. Typical fibrofibromas are densely organized, brightly white, bundled or vortexed with a clear boundary. The disease is rare, no significant gender differences, can occur in all ages, but clinically 90% of patients are under 30 years of age, no clear good hair, can occur in any bone of the entire skeletal system, in long bones (especially It is the femur, humerus and tibia. It is more common in the metaphysis. It is also found in the trunk. It often invades to the sacral end in adulthood. The symptoms are mild and occur late, including moderate pain, pathological fractures, and occasional bone swelling. basic knowledge The proportion of illness: 0.002% Susceptible people: no specific people Mode of infection: non-infectious Complications: osteofibrosarcoma

Cause

Fibroid fibroma etiology

1. Visible to the naked eye: The typical fibrofibromas are densely organized, brightly white, bundled or vortexed, with a clear boundary.

2. Seen under the microscope: it is a kind of fibrous tissue with different degrees of density and maturity. The ratio of fibroblasts to collagen fibers is different everywhere. There are not many fibroblasts and fibroblasts. The cells are small, the degree of maturity is different, and the nucleus is not full. The staining is not deep, the mitosis is like little or no, the collagen fiber is very rich, often forming a wavy band, and even a glass-like dense area. The boundary of the tumor is not as clear as the general pathology, and tends to dilute in the surrounding tissue.

Prevention

Fibroid fibroma prevention

There are no special and effective preventive measures, and some adjustments can be made in the diet to limit the intake of pickled, smoked, and nitrite-containing foods.

Complication

Fibrofibromatosis complications Complications osteofibrosarcoma

The area is prone to lumps after treatment.

Symptom

Symptoms of fibroid fibroma Common symptoms Skeletal surface outward protruding bone pain Long bone swelling and pain

The disease is rare, no significant gender differences, can occur in all ages, but at the time of diagnosis, 90% of patients are under 30 years of age, no clear good hair, can occur in any bone of the entire skeletal system, in the long bones (especially the femur, tibia and fibula) are more common in the metaphysis, but also in the backbone, often invaded to the sacral end in adulthood, mild symptoms, late, including moderate pain, pathological fractures, occasionally a considerable degree of bone Swell.

Examine

Fibroid fibroma examination

X-ray findings: due to lack of symptoms, fibrofibromas often reach a considerable volume in the first X-ray film, the image shows osteolytic lesions, sometimes regular, sometimes due to the presence of parenchyma Existence produces a foamy image, the cortical bone can be eccentrically thinned, or the entire cortical bone becomes thin.

Fibrofibromas are only moderate in arteriography and diffusely enhance staining, which is a relatively "cold area" on bone scans.

Diagnosis

Diagnosis and diagnosis of fibroblastoma

For a long-standing, large foam-like callus, osteolytic lesions without malignant features, the diagnosis of fibrofibromas should be suspected. In histology, fibroblasts must be differentiated from grade I fibrosarcoma. Grade I fibrosarcoma has more cells and more plump and polymorphic nuclei. Common mitotic figures. In fact, fibrofibromas and low-grade malignant fibrosarcoma do not have a clear distinction. In some cases, it is difficult. distinguish.

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