Angiosarcoma
Introduction
Introduction to angiosarcoma Angiosarcoma, also known as malignant hemangioendothelioma, is a malignant tumor that occurs from vascular endothelial cells or mesenchymal cells that differentiate into vascular endothelial cells. Tumor cells have the morphology and functional characteristics of normal endothelial cells to a certain extent. In the obvious malignant infiltration, the epithelial cells are obviously proliferated, the nucleus is abnormal, and the nuclear mitosis is more common. There are no or very few reticular fibers between cells, but there is still an envelope with unclear boundaries. Therefore, it is often impossible to determine the clinical condition from the changes in tumor histology. basic knowledge The proportion of illness: 0.001% Susceptible people: no specific population Mode of infection: non-infectious Complications: varicose veins
Cause
Angiosarcoma etiology
Cause:
In the vascular cavity and vascular buds arranged by endothelial cells, irregularly accumulating closely-gathered epithelial cells can be seen, and the cells are elliptical or fusiform. When the reticular fibers are stained, the reticular fibers surround the capillary endothelium. Around, while the tumor cells are around the reticular annulus, reticular fiber staining has considerable value for the diagnosis of this tumor. In the obvious malignant infiltration, the epithelial cells are obviously proliferated, the nucleus is abnormal, and the nuclear mitosis is more common. There are no or very few reticular fibers between cells, but there is still an envelope with unclear boundaries. Therefore, it is often impossible to determine the clinical condition from the changes in tumor histology.
Prevention
Angiosarcoma prevention
There is no effective preventive measure for this disease. Early diagnosis and early treatment are the key to the prevention and treatment of this disease. Try to be light, try to eat more nutritious products, use more vitamins and magnesium-rich foods, eat more vegetables and fruits, keep the ambassador smooth, prevent constipation, because of constipation, there is a huge tumor The danger of body rupture, avoid eating greasy and thick, spicy and irritating foods, such as peppers, seafood, barbecue, hard alcohol and spicy fried food.
Complication
Angiosarcoma complications Complications varicose veins
Angiosarcoma metastasizes, mainly through lymphatic and blood transfer.
Symptom
Angiosarcoma Symptoms Common symptoms Varicose telangiectasia Histiocytosis Proliferation Angiogenesis Hepatic sagging
Can occur at any age, more common in adults, a few congenital, occur in the skin, subcutaneous, muscle and bone tissue, can also occur in the oral cavity, mediastinum and retroperitoneal, etc., common in limbs, especially the lower extremities, followed by Torso, head, neck, usually single hair, different size, diameter 1 ~ 4cm, hard, nodular or plaque, normal skin surface, occasionally varicose veins or telangiectasia, sometimes benign The border is clear and the growth is slow, while the malignant grows fast and invasively grows, while others form metastasis, and the lung is most susceptible. In some cases, metastasis may occur several years after the skin tumor is removed. Lymphatic vessels or blood flow.
Examine
Angiosarcoma examination
Mainly by histopathological examination to confirm the diagnosis, the disease is different from single glomus tumor, the damage is large, the cell proliferation is irregular, the nucleus is polymorphous, and it is also different from Kaposi sarcoma, but the latter is more obvious vascular proliferation, endothelial cells More into the lumen, almost always red blood cell overflow, in malignant vascular endothelial cell tumor, the vascular lumen is more prominent, while the reticular fiber staining, it can be seen that the relationship between reticular fibers and tumor cells is completely different, can be distinguished.
Diagnosis
Diagnosis and diagnosis of angiosarcoma
Diagnosis should be noted with the identification of single glomus tumors, Kaposi sarcoma.
