mesenchymal chondrosarcoma
Introduction
Introduction to mesenchymal chondrosarcoma Mesenchymal chondrosarcoma is a rare malignant cartilage tumor that occurs mostly in young adults. Lichtenstein was the first report in 1959, and Dowling reported the first mesenchymal chondrosarcoma that originated in soft tissue in 1964, up to 200 cases reported in foreign literature in 1996. Pain, swelling, swelling, and joint stiffness that last for months to years are the main clinical symptoms of the disease. The invading bones are pelvis, femur, tibia, vertebral body, mandible and skull. basic knowledge The proportion of illness: 0.005% Susceptible people: mostly occur in young adults Mode of infection: non-infectious Complications: osteosarcoma chondrosarcoma
Cause
Cause of mesenchymal chondrosarcoma
Mostly originated from bone tissue, a few originated from soft tissue, dense round cell hyperplasia, like Ewing's sarcoma, lymphoma and vascular epithelioma, the cells are round or oval, these small cells have angiocarcinoma or The vesicular-like structure has large or small cartilage islands in the tissue. These cartilage-like regions have no malignant characteristics and often tend to be calcified-ossified.
Prevention
Mesenchymal chondrosarcoma prevention
Early detection and early diagnosis and early treatment are the key to prevention and treatment of this disease.
Complication
Mesenchymal chondrosarcoma complications Complications osteosarcoma chondrosarcoma
Clinically, in addition to the mass, the corresponding symptoms often appear due to tumor compression.
Symptom
Symptoms of mesenchymal chondrosarcoma common symptoms osteosclerosis fibrous membrane enveloping joint stiffness periostitis erosive bone destruction
The disease lasts for several months to several years. Pain, swelling, mass and joint stiffness are the main clinical symptoms of the tumor. According to 111 cases reported by Nakashima et al, the invading bones are pelvis, femur, humerus, vertebral body, mandible and Skull, occasionally there are reports of periosteal and skeletal multicentric tumor growth. The extramedullary tissue is mainly affected by the meninges, lower limbs and eyelids. The radiological changes of the tumor are mainly characterized by irregular soft tissue ossification and erosion. Bone destruction, osteosclerosis, periostitis, central calcification, etc., are similar to general chondrosarcoma in the radiological manifestations of tumors. The tumors vary in size and can be lobulated, with fibrous membranes on the surface, histology. The tumor is characterized by the mixing of hyaline cartilage islands and malignant small cells, mostly originating from bone tissue, and a few originating from soft tissue.
Examine
Examination of mesenchymal chondrosarcoma
X-ray findings are osteolytic lesions, penetrated and damaged by cortical bone, and there are often blurred calcifications in the tumor.
Diagnosis
Diagnosis and diagnosis of mesenchymal chondrosarcoma
diagnosis
Diagnosis can be based on medical history, clinical symptoms, and laboratory tests.
Differential diagnosis
Different from tumors of other soft tissues.
