Cerebral toxoplasmosis
Introduction
Introduction to cerebral toxoplasmosis Toxoplasma Chinese medicine is called three corpses and is an intracellular parasite. Parasitic in the cells, with the flow of blood, reaching all parts of the body, destroying the brain, heart, and fundus, causing people's immunity to decline, suffering from various diseases. It is an obligate intracellular parasite, a coccidia subclass, a true coccidia, a spore coccidia, and a toxoplasma. Toxoplasmosis is a brain parasitic disease caused by Toxoplasma gondii, which is the main cause of death from toxoplasmosis. basic knowledge Sickness ratio: 0.1% Susceptible people: no special people Mode of infection: fecal mouth spread Complications: hepatitis pneumonia pericarditis nephritis arthritis peritonitis
Cause
Causes of cerebral toxoplasmosis
Acquired cerebral toxoplasmosis is mainly caused by ingestion of uncooked meat, eggs and unsterilized milk containing Toxoplasma gondii; it can also be infected through skin, mucous membrane damage or transfusion, organ transplantation; contact with oocysts Polluted soil and water sources are also important routes of transmission. Arthropods (fly, cockroach) carrying oocysts also have a certain transmission significance.
Prevention
Cerebral toxoplasmosis prevention
1. Strengthen the monitoring and isolation of livestock, poultry and suspicious animals.
2. Strengthen the management of meat quarantine, food hygiene and cat raising, do not eat raw or half-lived meat, unsterilized dairy products, and routinely check the pregnant women for Toxoplasma gondii to prevent the occurrence of congenital toxoplasmosis.
Complication
Complications of cerebral toxoplasmosis Complications, hepatitis, pneumonia, nephritis, arthritis, peritonitis
1. Toxoplasma infection can cause damage to multiple tissues and multiple organs, often with some important organs such as the eye, and retinal choroiditis is more common.
2. If the patient's resistance is reduced, the acute spread of Toxoplasma gondii can often cause hepatitis, pneumonia, extensive myositis, pericarditis, nephritis, arthritis and peritonitis.
Symptom
Symptoms of cerebral toxoplasmosis common symptoms fatigue, increased intracranial pressure, small head pain, nausea, splenomegaly
First, medical history and symptoms:
1. The latency of acquired cerebral toxoplasmosis varies from 3 days to 2 years, but primary encephalopathy can also be part of systemic toxoplasmosis, which is more common in patients with low immune function. Clinical manifestations include meningitis, diffuse encephalopathy, seizures, intracranial lesions, or mental disorders.
2. Pregnant women with congenital cerebral toxoplasmosis can often cause miscarriage, premature birth or stillbirth after infection. Surviving infants may have dysplasia such as hydrocephalus, microcephaly, and mental retardation.
Some patients with toxoplasmosis may have fever, myalgia, fatigue, and lymph node hepatosplenomegaly. Choroiditis, iritis, retinitis, and the like may also occur.
Second, physical examination found:
1. Increased intracranial pressure may cause headache, nausea, vomiting, and fundus papilledema.
2. Patients with brain parenchymal damage may have hemiplegia and aphasia.
The cause of congenital cerebral toxoplasmosis refers to the infection of the fetus in the mother's placental blood.
Examine
Examination of cerebral toxoplasmosis
1. Lumbar puncture cerebrospinal fluid examination: lymphocytes mainly composed of lymphocytes, accompanied by increased eosinophils and protein.
2. Serum and cerebrospinal fluid were positive for anti-toxoplasma antibody test.
3. Head CT examination see single or multiple equal or low density lesions.
4. The diagnosis of toxoplasma trophozoites in cerebrospinal fluid, lymph nodes, and brain biopsy is confirmed.
Diagnosis
Diagnosis and diagnosis of cerebral toxoplasmosis
Diagnosis can be based on medical history, clinical symptoms, and laboratory tests.
Sometimes it needs to be differentiated from tuberculosis, cryptococcal meningitis, and herpetic meningoencephalitis. By pathogen examination, serum and cerebrospinal fluid anti-toxoplasma antibodies are positive, and it is not difficult to identify.
