subcutaneous lipid granulomatosis
Introduction
Introduction to subcutaneous lipid granulomatosis The disease, also known as Rothmann-Makai syndrome, was first reported in 1984. In 1928, Makai named the disease as subcutaneous lipid granulomatosis. The disease is rare, mainly in children. It is considered to be a type of nodular panniculitis. The nodules scattered, no atrophy and depression after regression, no systemic symptoms. According to the cause, clinical manifestations and blood routine examination can be diagnosed. The disease has a self-healing tendency, and the treatment plan for acute attacks can refer to nodular panniculitis. basic knowledge The proportion of illness: the incidence rate is about 0.05% - 0.07% Susceptible people: mainly in children Mode of infection: non-infectious complication:
Cause
The cause of subcutaneous lipid granulomatosis
Although some people think that trauma or vascular injury is related to the pathogenesis of this disease, this may be only an inducement. The exact cause is not clear. The early pathological changes are acute inflammation of fatty lobule, degeneration and necrosis of fat cells, and hooliganism. Infiltration of granulocytes, tissues and lymphocytes, fibrosis in the late stage, due to the majority of fat cells necrosis, there may be cysts of different sizes in the tissue, the wall of the capsule is connective tissue, and there is calcium salt deposition inside.
Prevention
Subcutaneous lipid granulomatosis prevention
As the cause is unclear, there are currently no effective preventive measures.
Complication
Subcutaneous lipid granulomatosis complications Complication
The disease has a self-healing tendency and generally has no complications.
Symptom
Symptoms of subcutaneous lipid granulomatosis common symptoms subcutaneous nodular skin adhesions
The basic damage is nodules or plaques, the nodules are usually 0.5-3cm, but the larger ones can reach 10-15cm, the quality is harder, the surface skin color is light red or political house skin color, subjective feeling is absent, only It has mild tenderness and uneven number of nodules. It is scattered on the face, trunk and limbs. It is more common in the thigh extension. The nodules gradually retreat after 6 months to 1 year, without atrophy. In the depression, the nodules of a few cases can last for several years without systemic symptoms such as fever .
Examine
Examination of subcutaneous lipid granulomatosis
Blood test.
Diagnosis
Diagnosis and diagnosis of subcutaneous lipid granulomatosis
The diagnosis of this disease is clear and does not need to be identified with other diseases.
