salivary adenovirus disease
Introduction
Introduction to Parotid Disease The virusdiseaseofsalivarygland is also called cytomegalic inclusion disease, which is caused by cytomegalovirus infection. The virus can exist for a long time in the human body and is discharged from saliva or urine. The infection route is mainly contact infection, and the infant can be infected through the placenta. More common in the submandibular glands and parotid glands. basic knowledge The proportion of illness: 0.060% Susceptible people: young children Mode of infection: contact infection Complications: hemolytic anemia thrombocytopenic purpura jaundice
Cause
The cause of adenoviral disease
The disease is caused by cytomegalovirus infection. The virus can exist for a long time in the human body and is discharged from saliva or urine. The infection route is mainly contact infection. Infants and young children can be infected through placenta, which is more common in the submandibular gland and parotid gland.
Prevention
Parotid virus disease prevention
Cytomegalovirus is very harmful to humans, so we should actively prevent it from happening.
(1) Carry out conscious physical exercise, improve the body's immune function and disease resistance, especially women of childbearing age, to reduce the serious harm of cytomegalovirus to the fetus.
(2) For pregnant women or patients with chronic wasting diseases, patients with low immunity should pay attention to protection and keep them away from the source of infection.
(3) Pay attention to environmental hygiene and food hygiene.
(4) Those who are positive for cytomegalovirus in milk should not breastfeed.
(5) Immunological control is still under research and exploration.
Complication
Complications of parotid virus disease Complications hemolytic anemia thrombocytopenic purpura jaundice
There may be obvious hepatosplenomegaly, hemolytic anemia, jaundice, thrombocytopenic purpura and nervous system involvement, and the immune response is abnormal.
Symptom
Symptoms of parotid virus disease Common symptoms Huangqi liver splenomegaly fever thrombocytopenia
Infants that occur more than two years old can occur in adults, but it is rare. Fetuses with placenta infections are stunted and can cause premature birth. There are no special symptoms or signs in the clinic, and there may be obvious hepatosplenomegaly. , hemolytic anemia, jaundice, thrombocytopenic purpura and nervous system violations, however, because this disease has no special symptoms, it is often found at autopsy, there are reports of 10% to 30% of the parotid gland The manifestations of physical illness, adults are related to extreme weakness of the body, the most common clinical manifestations are fever, hepatic gland enlargement and lymphocytosis, and abnormal immune response during infection.
Examine
Examination of parotid virus disease
Sputum, sputum, urine check.
It is characterized by the presence of characteristic cells in sputum, sputum, and urine. It is characterized by the appearance of inclusion bodies in the ductal epithelial cells. The cells are large, with a diameter of up to 30 m, and a large nucleus with a diameter of 10 to 15 m. Located in the basal part of the cell, the inclusion body is in the nucleus, or on the luminal side of the cytoplasm, which is round, most of which is eosinophilic, positive for acid mucopolysaccharide staining, and lymphocytes around the inclusion body cells. Plasma cells, mononuclear cells infiltrated, and cells containing inclusion bodies can be denatured, stripped, and collapsed.
Diagnosis
Diagnosis and diagnosis of parotid virus disease
Diagnosis can be based on medical history, clinical symptoms, and laboratory tests.
Need to be differentiated from neonatal hemolysis.
Neonatal hemolysis is mainly caused by maternal and child blood group incompatibility or infants suffering from erythrocyte glucose-6-phosphate dehydrogenase deficiency, manifested as jaundice, anemia, edema, hepatosplenomegaly, etc. Once hypoxic, contact mothballs, Hemolysis can be induced by taking sulfa drugs and injecting vitamin K.
The immune hemolytic disease caused by the incompatibility of the mother and child blood type is called neonatal hemolytic disease, and the blood type of the mother and child is not compatible with the Rh blood group system of the ABO blood group system.
The mother of ABO blood group incompatibility with hemolytic disease is generally O-type, and the fetus is mainly type A or B. The occurrence of the fetus is not related to the parity, that is, the first fetus may be ill. It is suggested that the ABO blood group incompatibility rate is 27.7. %, the incidence of neonatal ABO blood group incompatibility is 11.9%, then why are the same blood type, some hemolysis, some do not hemolysis? At present, there is no possible situation for this problem, after the mother is pregnant, If the fetal red blood cells do not enter the mother's body or the mother's body is very small enough to stimulate the mother to produce antibodies, it will not occur, of course, there are other reasons.
Neonatal hemolytic disease caused by Rh blood group incompatibility occurs in Rh-negative mothers. The fetus is Rh-positive, generally occurring in the second child. If the mother has a history of blood transfusion, the first-born disease can also occur. After the first onset, hemolytic disease occurs in each fetus. And getting heavier and heavier, Rh hemolytic disease is more serious than ABO hemolytic disease.
