eosinophilic adenoma
Introduction
Introduction to eosinophilic adenoma Oxyphilicadenoma, also known as macrocoagulony, is a rare benign tumor of the parotid gland. The histogenesis of eosinophilic adenomas is not fully understood and may come from ductal epithelium or ductal myoepithelial cells. basic knowledge The proportion of illness: 0.02% Susceptible people: no special people Mode of infection: non-infectious complication:
Cause
Eosinophilic adenoma
The histogenesis of eosinophilic adenomas is not fully understood and may come from ductal epithelium or ductal myoepithelial cells.
Pathological change
1. Gross-shaped tumors are generally round or elliptical, with a smooth surface, individual nodular, enveloped and intact, with a brown cross section, no cystic changes, hemorrhagic or mucoid-like areas.
2. Microscopic examination of tumor cells with large volume, clear boundaries, round or polygonal, cytoplasm granules, eosinophilic staining, nuclear round or oval, deep staining, even pyknosis, nucleoli visible, but mitotic figures Very rare, ultrastructural studies have found that these eosinophils are filled with enlarged and deformed mitochondria, which are arranged in solid trabeculae or masses, sometimes in a glandular lobular arrangement, but do not form a glandular lumen, a tumor cell mass There is a fibrous connective tissue interstitial, which separates the epithelial mass into leaves, no lymphoid tissue in the interstitium, or occasionally a small amount of lymphocytes, but generally does not form lymphoid follicles.
3. Biological characteristics Eosinophilic adenomas are benign tumors with small tumors, slow growth, no recurrence after complete resection, and rarely malignant changes.
Prevention
Eosinophilic adenoma prevention
There is no report on prevention methods, and early detection and early diagnosis are the key.
Complication
Eosinophilic adenoma complications Complication
It can also have pituitary eosinophilic adenomas, renal eosinophils and other diseases.
Symptom
Eosinophilic adenoma symptoms Common symptoms Nodular growth slow parotid painless mass
Clinical manifestation
Eosinophilic adenomas mainly occur in the parotid gland, accounting for less than 1% of parotid tumors, mostly unilateral, and individual cases can also occur on both sides, sometimes in submandibular glands, parotid glands, buccal glands, etc., often occurring in older women. The age of onset is more than 50 years old, and 80% occurs between 50 and 60 years old.
Eosinophilic adenoma is a clinical manifestation of benign tumors. The tumor volume is generally small, the diameter is generally less than 5cm, the growth is slow, the patient has no discomfort, the tumor is round or oval, the activity is soft, and the skin is non-adhesive. .
The eosinophil mitochondrial oxidase system of the parotid gland has an affinity for 99m, which can cause hot nodules in 99m isotope scans of eosinophilic adenomas.
Examine
Examination of eosinophilic adenoma
The eosinophil mitochondrial oxidase system of the parotid gland has an affinity for 99m, which can cause hot nodules in 99m isotope scans of eosinophilic adenomas.
Diagnosis
Diagnosis and identification of eosinophilic adenoma
Diagnosis can be based on medical history, clinical symptoms, and laboratory tests.
Differential diagnosis
Identification with mumps:
Mumps is an acute respiratory infection caused by mumps virus invading the parotid gland. The patient is the source of infection. Inhalation of droplets is the main route of transmission. It occurs 2-3 weeks after exposure to the patient. Mumps is mainly manifested under one or both sides of the earlobe. The swollen, swollen parotid gland is often hemispherical, with the earlobe as the center of the edge is unclear, the surface is hot and angular pain, and the mouth is painful when opening or chewing. The swelling of the parotid gland is most obvious in the first 1-3 days of onset, and gradually subsides. The swelling in 2 weeks is completely exhausted. In the early 3-5 days of the onset of the disease, there may be fever, fatigue, and unwillingness to eat and other systemic symptoms.
