papillary cystadenocarcinoma
Introduction
Introduction to papillary cystadenocarcinoma Papillary cystatic adenocarcinoma (papillary cystadenocarcinoma) is relatively rare in parotid tumors, accounting for 5% to 7% of parotid epithelial tumors, and is often considered a subtype of adenocarcinoma. Eneroth et al. refer to this type of tumor as "mucus producing adenopapillary carcinoma", which is derived from the parotid ductal epithelium. basic knowledge Sickness ratio: 0.001%-0.0025% Susceptible population: The age of onset is 12 to 72 years old, with an average of 42.5 years old. It is more common in 30 to 50 years old, and the ratio of male to female is 2:1. Mode of infection: non-infectious Complications: facial paralysis
Cause
The cause of papillary cystadenocarcinoma
(1) The gross morphology of the tumor looks like a mixed tumor, which is round or nodular, with no membrane. The tumor section is usually cystic, the inner wall of the cavity is not smooth, and there may be some papillary protrusions or granular.
(B) microscopic examination of cancer cells of different sizes, column or cuboid, and the formation of a variety of irregular adenoid structures, many of which significantly expand into a saclike shape, cell arrangement disorder, although single or multi-layered, And the cancer cells are extremely hyperplasia, forming a single or dendritic nipple, protruding into the cystic cavity, the cytoplasm of the cancer cells is slightly basophilic, the nucleus is large, the morphology is different, the staining is deep, and the nucleus is more, between the cancer cells or the nipple. For a small amount of fibrous tissue interstitial, there is often inflammatory cell infiltration, but no lymphoid tissue, tumor capsule is incomplete, and sometimes tumor cells invade into or around the tissue.
(C) Biological characteristics Papillary cystadenocarcinoma grows fast and slow, can follow the blood line, lymphatic metastasis, can also violate the nerves.
Prevention
Papillary cystadenocarcinoma prevention
There are no effective preventive measures for this disease. Early detection and early treatment are the key to prevention.
Complication
Papillary cystadenocarcinoma Complications
Can be secondary to local lymphadenopathy, skin ulceration, facial paralysis, bone destruction and so on.
Symptom
Papillary cystic gland cancer symptoms Common symptoms Smoothness and toughness in the breast... Breast lumps Gallbladder wall thinning Breast pain Breast redness and heat pain
Papillary cystadenocarcinoma is most common in the parotid gland, followed by the small parotid gland and submandibular gland, buccal mucosa, mouth, tongue and upper lip. The parotid gland can also occur. According to Dong Shaozhong, the age of onset is 12 to 72 years old. The average is 42.5 years old, more common in 30 to 50 years old, the ratio of male to female is 2:1.
Tumor-like malignant mixed tumor, the common symptom is a local painless mass, which grows faster, some grows larger, is nodular, and can form a saclike shape due to the obvious enlargement of the glandular cavity, and hemorrhage and necrosis can occur. Cystic changes occur, the palpation part is soft, and the puncture can draw hemorrhagic secretions. Generally, there is no obvious adhesion in the early stage, activity, growth with the tumor, activity is getting worse, adhesion to surrounding tissues occurs, and it is easy to invade the deep adjacent tissues. Including the chewing muscles and the mandible, the pain and facial nerve involvement often occur in the late stage.
Examine
Examination of papillary cystadenocarcinoma
Breast examination is a physical examination of the breast, and screening of breast diseases, early detection, early diagnosis and early treatment, is very important in the treatment of breast disease prevention. Normal breast examination: no abnormal mass was found in the examination.
Breast Tumor Marker (CA 15-3): CA 15-3 is an auxiliary examination for breast cancer. CA 15-3 check normal, must not neglect breast self-examination. The most important thing to prevent and treat breast cancer is self-examination. If you have doubts, you should seek medical attention immediately and further do mammography. Because the positive rate of CA 15-3 is only about 50%, it should be carefully interpreted by professionals when screening. Do not interpret it by yourself. Mammary tumor marker (CA 15-3) normal value: normal female serum CA15-3 value (22.22 ± 16.31) u / ml.
The diagnosis is mainly based on histopathological examination.
Diagnosis
Diagnosis and differentiation of papillary cystadenocarcinoma
diagnosis
Diagnosis can be based on medical history, clinical symptoms, and laboratory tests.
Differential diagnosis
To identify whether the tumor is benign or malignant, and to identify whether it is from the parotid gland or the submandibular gland.
