primary IgA nephropathy
Introduction
Introduction to primary IgA nephropathy Primary IgA nephropathy (inflammation) is the diagnostic name for immunopathology. It is characterized by recurrent episodes of gross hematuria or microscopic hematuria, which may be associated with varying degrees of proteinuria. Renal tissue is characterized by IgA-based immunoglobulin deposition. basic knowledge The proportion of illness: 0.21% Susceptible people: no special people Mode of infection: non-infectious Complications: abdominal pain, hematuria, proteinuria, hypertension, edema
Cause
The cause of primary IgA nephropathy
The iga-based immunoglobulin deposition is caused by upper respiratory tract infection (or acute gastroenteritis, peritonitis, osteomyelitis, etc.) 1 to 3 days later.
Prevention
Primary IgA nephropathy prevention
Prevent colds and overwork, use nephrotoxic drugs with caution, antibiotics should be treated when there is infection, and chronic tonsillitis should be repeated, and tonsils can be removed.
Complication
Primary IgA nephropathy complications Complications abdominal pain hematuria proteinuria hypertension edema
May be associated with abdominal pain, low back pain, muscle pain or low fever, a small number of patients with persistent gross hematuria and varying degrees of proteinuria, may be associated with edema and high blood pressure.
Symptom
Symptoms of primary IgA nephropathy Common symptoms Small blood vessel fibrosis necrosis Hypertension Low fever Abdominal pain Kidney area Sickness glomeruli Pathological changes Proteinuria Hematuria
First, medical history and symptoms
More often in the upper respiratory tract infection (or acute gastroenteritis, peritonitis, osteomyelitis, etc.) 1 to 3 days after the recurrence of gross hematuria, for several hours to several days can be converted to microscopic hematuria, may be associated with abdominal pain, low back pain, Muscle pain or low fever, some patients found abnormal urine during physical examination, asymptomatic proteinuria and (or) microscopic hematuria, a small number of patients with persistent gross hematuria and varying degrees of proteinuria, may be associated with edema and high blood pressure.
Second, physical examination found
Most of them have no abnormal signs. Some patients may have sputum pain in the two kidney areas, edema and mild, and moderate blood pressure.
Third, auxiliary inspection
Mostly mild, moderate proteinuria (<3g/d), hematuria is pleomorphic, diverse or mixed, some patients have increased serum IgA, especially serum IgA fibronectin polymer (IgA-FN) increased Significance, there may be a decrease in creatinine clearance, blood urea nitrogen and serum creatinine, according to the clinical diagnosis of IgA nephropathy (inflammation), kidney tissue immunopathology must be confirmed.
Examine
Examination of primary IgA nephropathy
Mostly mild, moderate proteinuria (<3g/d), hematuria is pleomorphic, diverse or mixed, some patients have increased serum IgA, especially serum IgA fibronectin polymer (IgA-FN) increased Significance, there may be a decrease in creatinine clearance, blood urea nitrogen and serum creatinine, according to the clinical diagnosis of IgA nephropathy (inflammation), kidney tissue immunopathology must be confirmed.
Diagnosis
Diagnosis and diagnosis of primary IgA nephropathy
Diagnosis can be based on medical history, clinical symptoms, and laboratory findings.
Should be differentiated from lupus nephritis, purpuric nephritis, occult nephritis, severe and chronic glomerulonephritis is difficult to identify.
