Urinary thromboxane B2

Thromboxane (TXA2) is a type of prostaglandin that is produced by platelets and has platelet aggregation and vasoconstriction. In contrast to prostacyclin, the two are dynamically balanced to maintain vasomotor function and platelet aggregation. TXA2 has a biological half-life of only 30 s and is rapidly converted to inactive thromboxane B2 (TXB2). Basic Information Specialist classification: urinary examination classification: urine / kidney function test Applicable gender: whether men and women apply fasting: not fasting Analysis results: Below normal: In patients with chronic renal failure, TXB2 and 6-keto-PGF1α decreased in the urine. Normal value: Urinary thromboxane B2: 123.9-224.3pg/min Above normal: There was a significant increase in TXB2 in hemorrhage, injury, and endotoxin shock plasma. negative: Positive: Tips: Try to use fresh morning urine when doing this check. The urine that is randomly selected is preferably mid-stage urine. Menstrual women are not suitable for this examination. Normal value Urine (174.1 ± 50.2) pg / min. Clinical significance Changes in thromboxane levels are seen in atherosclerosis, angina pectoris, coronary heart disease, diabetes, hyperlipidemia, etc. Increased TXA2/PGI2 ratio is prone to platelet aggregation, thrombosis, and atherosclerosis and coronary heart disease. There was a significant increase in TXB2 in hemorrhage, injury, and endotoxin shock plasma, which was associated with increased pulmonary circulation resistance during shock. In patients with chronic renal failure, TXB2 and 6-keto-PGF1α decreased in the urine. There were also significant changes in urinary PG in patients with renal vascular hypertension, nephrotic syndrome, and Batter syndrome. TXA2 is altered in arterial tissue of patients with malignant tumors. When PGI2 and TXA2 are normal, it can prevent tumor cells from invading platelets and adhering to the surface of blood vessels. Factors that inhibit platelet TXA2 production and increase vascular endothelial cell PGI2 production have anti-tumor metastatic effects. Low results may be diseases: high results of chronic renal failure may be diseases: coronary heart disease, diabetes considerations Note during inspection: Fresh morning urine should be used as much as possible during this examination. The urine that is randomly selected is preferably mid-stage urine. Not suitable for the crowd: menstrual women. Inspection process Inspection process: As with routine urine tests, use a clean, dry container with a disposable urine cup and urine test tube provided by the hospital. Take about 10 ml of urine and send it to the designated inspection window of the hospital for examination by a doctor. Not suitable for the crowd Menstrual women. Adverse reactions and risks no.