Urine Ketones (KET)

The ketone body is a general term for acetoacetic acid, β-hydroxybutyric acid and acetone. It is an intermediate metabolite produced by human body using fatty oxides. The ketone bodies produced by normal people are quickly utilized, and the content in blood is extremely small, about 2.0- 4.0 mg / L, wherein the various additions of acetoacetate beta hydroxybutyrate acetone accounted for about 20%, 78%, 2%. The ketone body in urine (in terms of acetone) is about 50 mg / 24 h. The qualitative test is negative. However, in the case of hunger, various causes of glucose metabolism, increased lipid decomposition and diabetic acidosis, ketoneemia may occur due to the ketone body velocity being greater than the tissue utilization rate, followed by ketonuria (KET). Basic Information Specialist classification: urinary examination classification: urine / kidney function test Applicable gender: whether men and women apply fasting: not fasting Analysis results: Below normal: Normal value: no Above normal: negative: normal. Positive: 1, diabetic ketoacidosis due to reduced sugar utilization, decomposition of fat to produce increased ketone body and cause ketosis. Urine ketone body testing is extremely valuable when there is acidosis or coma in uncontrolled or improperly treated diabetes. It should be distinguished from hypoglycemia, heart and brain disease lactic acidosis or hyperglycemia and high permeability diabetes coma. In the case of ketoacidosis, the ketone body is positive, while the latter urinary ketone body generally does not increase, but it should be noted that diabetic ketosis suffers from severe renal damage and the renal threshold increases, the urinary ketone body can also be reduced or even completely disappeared. 2, non-diabetic ketosis such as infectious diseases such as pneumonia, typhoid fever, sepsis, tuberculosis, etc., severe diarrhea, vomiting, dehydration, hunger, strenuous exercise, fasting for a long time, after the body anaesthesia, etc. This situation is quite common. Pregnant women often have urinary ketone body positive due to pregnancy reaction, vomiting, eating less, and pregnancy-induced hypertension. 3, poisoning such as chloroform, ether anesthesia, phosphorus poisoning and so on. 4, taking biguanide pills, such as Jiangtangling, because the drug has the effect of inhibiting cellular respiration, blood sugar has decreased, but the urine ketone body is positive. Tips: Try to use fresh morning urine when doing this check. The urine that is randomly selected is preferably mid-stage urine. Menstrual women are not suitable for this examination. Normal value The qualitative test was negative and was recorded as (-). Clinical significance Positive, can be seen in the following situations: 1, diabetic ketoacidosis due to reduced sugar utilization, decomposition of fat to produce increased ketone body and cause ketosis. Urine ketone body testing is extremely valuable when there is acidosis or coma in uncontrolled or improperly treated diabetes. It should be distinguished from hypoglycemia, heart and brain disease lactic acidosis or hyperglycemia and high permeability diabetes coma. In the case of ketoacidosis, the ketone body is positive, while the latter urinary ketone body generally does not increase, but it should be noted that diabetic ketosis suffers from severe renal damage and the renal threshold increases, the urinary ketone body can also be reduced or even completely disappeared. 2, non-diabetic ketosis such as infectious diseases such as pneumonia, typhoid fever, sepsis, tuberculosis, etc., severe diarrhea, vomiting, dehydration, hunger, strenuous exercise, fasting for a long time, after the body anaesthesia, etc. This situation is quite common. Pregnant women often have urinary ketone body positive due to pregnancy reaction, vomiting, eating less, and pregnancy-induced hypertension. 3, poisoning such as chloroform, ether anesthesia, phosphorus poisoning and so on. 4, taking biguanide pills, such as Jiangtangling, because the drug has the effect of inhibiting cellular respiration, blood sugar has decreased, but the urine ketone body is positive. Positive results may be diseases: pregnancy vomiting, non-ketotic hyperglycemia - hyperosmolar coma, diabetes precautions Note during inspection: Fresh morning urine should be used as much as possible during this examination. The urine that is randomly selected is preferably mid-stage urine. Not suitable for the crowd: menstrual women. Inspection process Inspection process: As with routine urine tests, use a clean, dry container with a disposable urine cup and urine test tube provided by the hospital. Take about 10 ml of urine and send it to the designated inspection window of the hospital. Not suitable for the crowd Menstrual women. Adverse reactions and risks no.