Urinary β-galactosidase

Beta-galactosidase is a hydrolase in cell lysosomes and is high in renal proximal tubular epithelial cells. Urine beta-galactosidase activity can reflect the renal parenchyma, especially the early damage of the renal tubules, together with the urine N-acetyl β-D-glucosaminidase for urine zymography analysis, contribute to the course of disease observation and prognosis Evaluation. Basic Information Specialist classification: growth and development check classification: urine / kidney function test Applicable gender: whether men and women apply fasting: fasting Tips: In the field of genetics, it is of great significance for the diagnosis of human β-galactosidase deficiency disease. Normal value 2.51 to 14.3iu/L. (colorimetric method) Clinical significance The urinary β-galactosidase and N-acetyl β-D-glucosaminidase are lytic enzymes in the cytolysin, mainly derived from renal tubular epithelial cells, and thus are sensitive to tubular damage and acquired kidney disease. reaction. In the different stages of renal parenchymal injury, there are some differences in the discharge rate curve. It can be used for zymography analysis, which can be helpful for clinical diagnosis and evaluation, such as differential diagnosis of various nephropathy, toxicity of drugs to kidney, infection. Early detection of diseases such as shock, renal transplant rejection, acute tubular necrosis, etc., is a good indicator. Precautions In the field of genetics, it is of great significance for the diagnosis of human β-galactosidase deficiency disease. Inspection process NAG colorimetry. Not suitable for the crowd There are no taboos. Adverse reactions and risks No.

Was this article helpful?

The material in this site is intended to be of general informational use and is not intended to constitute medical advice, probable diagnosis, or recommended treatments.