4-Hydroxy-3-methoxymandelic acid

3-methoxy-4-hydroxymandelic acid, also known as vanillyl mandelic acid, is the final metabolite of adrenaline and norepinephrine, excreted from the urine, and urine 3-methoxy-4-hydroxymandelic acid is measured for diagnostic Chromoblastoma has a certain meaning. Basic Information Specialist classification: Oncology examination classification: urine / kidney function test Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Found in hyperthyroidism, coronary atherosclerosis and so on. Normal value: 4-hydroxy-3-methoxymandelic acid: 5-45μmol/24h Above normal: Found in pheochromocytoma, neuroblastoma, myocardial infarction, essential hypertension, chronic renal failure, and hypothyroidism. negative: Positive: Tips: If using fluorescence analysis, subjects should fast off items containing fluorescent reactions such as tea, coffee, chocolate, eggplant, tomato, banana, lemon juice, etc. 3 days before the test. Normal value 5 to 45 μmol / 24 h. Clinical significance Reduced in hyperthyroidism, coronary atherosclerosis and so on. Elevation is seen in pheochromocytoma, neuroblastoma, myocardial infarction, essential hypertension, chronic renal failure, and hypothyroidism. Low results may be diseases: hyperthyroidism, neuroblastoma results are high may be diseases: pheochromocytoma, myocardial infarction, coronary atherosclerotic heart disease considerations (1) use of vitamin C, vitamin B2, chlorpromazine, ampicillin, adrenaline, chloral hydrate, methyldopa, tetracycline, diazepam, caffeine, reserpine, meperidine and antihypertensives Etc. can affect the measurement results. (2) If fluorescence analysis is used, the subject should fast off the items containing fluorescent reactions such as tea, coffee, chocolate, eggplant, tomato, banana, lemon juice, etc. 3 days before the test. (3) After strenuous exercise, the results of the mentally stressed person can be increased. Inspection process Take 30 ml of concentrated HCl 10 ml anti-corrosion 24 h mixed urine, put into a 50 ml milled tip centrifuge tube, add concentrated HCl 3 ml, active magnesium silicate 3 g, shake for 10 min. Filter or centrifuge and collect the filtrate (supernatant) for use. The following extraction and color development. Mix and place in an ice water bath for 5 min. The wavelength of 495 nm is determined by the reagent blank O. Not suitable for the crowd There are no taboos. Adverse reactions and risks No.