Cerebrospinal fluid glucose to serum glucose ratio

The ratio of glucose in normal cerebrospinal fluid to glucose in the blood is thought to be due to the blood-brain barrier being able to penetrate glucose; it was later recognized that this permeability is not a simple diffusion, but a membrane operation called carrier operation or Carrying the dispersion, the glucose content in the cerebrospinal fluid depends on the following factors: 1 blood glucose concentration; 2 blood-brain barrier permeability; 3 the degree of glycolysis in the cerebrospinal fluid; 4 carrying the function of the operating system. Serum glucose measurement is one of the most important tests for the diagnosis of diabetes. Diabetic patients have varying degrees of elevated serum glucose. Basic Information Specialist classification: examination classification: cerebrospinal fluid examination Applicable gender: whether it is fasting: Analysis results: Below normal: Reduce bacterial meningitis, fungal meningitis, syphilitic meningitis, neoplastic meningitis, etc.; sarcoidosis (sarcomatosis), systemic lupus erythematosus, foreign body inflammation, subarachnoid hemorrhage (10 days) Within 25%, mumps, blister encephalitis, etc. 25% reduction. Normal value: Newborns and babies: 0.8-1.0 Adult: 0.6-0.7 Above normal: No relevant information. negative: Positive: Tips: The examinee should stop taking epinephrine, isoproterenol, meperidine, nicotine, aspirin and other drugs, and maintain a reasonable diet and rest. Normal value Newborns and babies 0.8 to 1.0. Adults 0.6 to 0.7. Clinical significance Abnormal results: Reduced in bacterial meningitis, fungal meningitis, syphilitic meningitis, neoplastic meningitis, etc.; sarcoidosis (sarcomatosis), systemic lupus erythematosus, foreign body inflammation, subarachnoid hemorrhage (10 Within 2 days), 25% of mumps, blister encephalitis, etc. People who need to be tested: People who have high fever, vomiting, lethargy, coma, and convulsions. Low results may be diseases: fungal meningitis considerations Before the test: The examinee should stop taking epinephrine, isoproterenol, pethidine, nicotine, aspirin and other drugs, and maintain a reasonable diet and rest. At the time of examination: venous blood was taken from the fasting after 8 to 12 hours of fasting, and the specimen was sent for examination within 1 hour. Inspection process Determination of cerebrospinal fluid glucose, protein and chloride biochemical analyzers by biochemical analyzer is mainly to detect various components in serum. Therefore, the quantitative determination of cerebrospinal fluid glucose, protein and chloride ions by biochemical analyzer meets clinical needs, both fast and accurate. The method is feasible. The urine analyzer uses dry chemical method to detect glucose. The detection range is 5～220mmol/L, the sensitivity is 2～5mmol/L, and large doses of penicillin and levodopa can cause false negatives; the glucose content in cerebrospinal fluid is only 2.5～4.5mmol/ L, most of the pathological conditions are lower, the dry chemical method can only be measured between -~+, and the diagnostic ability is poor. Not suitable for the crowd 1. If there is obvious papilledema or cerebral palsy, contraindications are contraindicated. 2. Patients who are in shock, exhaustion or endangered state and local skin inflammation, and lesions in the posterior cranial fossa are contraindicated. Adverse reactions and risks If the patient has symptoms such as breathing, pulse, or abnormal color during puncture, stop the operation immediately and deal with it accordingly.