cerebrospinal fluid cholesterol ester

The main components of lipids in cerebrospinal fluid are cholesterol, cholesterol esters, neutral fats, phospholipids (lecithin, myelin, etc.), fatty acids, glycolipids, etc., which are rare in nerve tissue damage, degeneration and demyelinating diseases. increase. Basic Information Specialist classification: neurological examination classification: cerebrospinal fluid examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: No relevant information. Normal value: Cholesterol cholesterol: 0.0358-0.0512mmol/L Above normal: Common in patients with cerebrovascular disease and have high blood pressure. negative: Positive: Reminder: TC measurement requires standardization, consistent with international standards, must have accurate and reliable standard reference material (SRM). Normal value 0.0435 ± 0.0077 mmol / L. Clinical significance Cerebrovascular disease patients have hypertensive cerebrospinal fluid cholesterol ester and free cholesterol significantly increased, and the reference values ​​of cholesterol ester and free cholesterol are 0.0435±0.0077mmol/L and 0.092±0.018mmol/L, respectively, and the former is elevated; Patients with cerebral arteriosclerosis also increased significantly, but mainly increased free cholesterol, so the detection of these two has a differential diagnosis. High results may be diseases: cerebrovascular disease considerations (1) The free Chol assay is rarely used clinically. If the free Chol is to be determined, the easiest method is to use the enzymatic method, that is, the CEH can be omitted in the above-mentioned TC assay enzyme reagent, and the general free Chol accounts for about TC. About 30%. (2) TC measurement requirements are standardized, and consistent with international standards, accurate and reliable standard reference materials (SRM) must be available. Inspection process Enzyme analysis method. Not suitable for the crowd 1. If there is obvious papilledema or cerebral palsy, contraindications are contraindicated. 2. Patients who are in shock, exhaustion or endangered state and local skin inflammation, and lesions in the posterior cranial fossa are contraindicated. Adverse reactions and risks If the patient has symptoms such as breathing, pulse, or abnormal color during puncture, stop the operation immediately and deal with it accordingly.