Serum aldosterone (ALD, ALS)

The action of aldosterone is to promote the reabsorption of sodium by the renal distal convoluted tubule epithelial cells and promote the excretion of potassium. The secretion of aldosterone has a diurnal secretion pattern similar to cortisol, which is lower in the morning than in the night. The standing position is increased compared with the lying position, and the plasma concentration is also changed accordingly. Basic Information Specialist classification: growth and development examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Found in aldosterone reduction, anterior pituitary dysfunction and adrenal insufficiency, as well as intake of anticonvulsants, deoxycorticosterone, propranolol (propranolol) and other drugs. Normal value: Serum aldosterone (position): 5 ng / dl - 15 ng / dlng / dl Serum aldosterone (recumbent position): 1 ng / dl - 5 ng / dlng / dl Above normal: Found in primary aldosteronism, congestive heart failure, cirrhosis with ascites, nephrotic syndrome and pregnancy toxemia, taking angiotensin, furosemide (furosemide), oral contraceptives and other drugs, and limiting sodium , potassium diet. negative: Positive: Tips: Do not eat too greasy, high-protein foods the day before the blood draw, avoid heavy drinking. The alcohol content in the blood directly affects the test results. After 8 pm on the day before the medical examination, fasting should be done to avoid affecting the detection of indicators such as blood glucose in the second sky. Normal value The standing position is 138 to 415 pmol/L (5 to 15 ng/dl). The lying position is 27.7 to 138.5 pmol/L (1 to 5 ng/dl). Clinical significance Increased in primary aldosteronism, congestive heart failure, cirrhosis with ascites, nephrotic syndrome and pregnancy toxemia, taking angiotensin, furosemide (furosemide), oral contraceptives and other drugs, and restrictions Sodium and potassium diets. Reduced in aldosterone reduction, anterior pituitary dysfunction and adrenal insufficiency, as well as intake of anticonvulsants, deoxycorticosterone, propranolol (propranolol) and other drugs. The result is low, the disease may be high: the result of adrenal insufficiency is high. Possible disease: Adrenal tumor considerations First, the precautions before blood draw 1, before the physical examination diet to control sodium and potassium, the standard diet is: intake of 100mmol sodium, 60 ~ 100mmol potassium. Limiting the absorption of sodium and potassium will result in higher assay results. 2, should relax when taking blood, to avoid the contraction of blood vessels caused by fear, increase the difficulty of blood collection. Second, should pay attention after blood draw 1. After blood is drawn, local compression is required at the pinhole for 3-5 minutes to stop bleeding. Note: Do not rub, so as not to cause subcutaneous hematoma. 2, the pressing time should be sufficient. There is a difference in clotting time for each person, and some people need a little longer to clotting. Therefore, when the surface of the skin appears to be bleeding, the compression is stopped immediately, and the blood may be infiltrated into the skin due to incomplete hemostasis. Therefore, the compression time is longer to completely stop bleeding. If there is a tendency to bleed, the compression time should be extended. 3, after the blood draw symptoms of fainting such as: dizziness, vertigo, fatigue, etc. should immediately lie down, drink a small amount of syrup, and then undergo a physical examination after the symptoms are relieved. 4. If there is localized congestion, use a warm towel after 24 hours to promote absorption. Inspection process Radioimmunoassay. Not suitable for the crowd People with reduced hematopoietic function such as leukemia, various anemia, myelodysplastic syndrome, or people with thrombocytopenia should pay attention to blood draw, and should not take more or more blood. Adverse reactions and risks 1. After the blood is drawn, do not press the needle hole to avoid subcutaneous hematoma. If there is a small piece of bruise in the blood, it is slightly tender, please don't panic, you can do hot compress after 24 hours to promote the absorption of blood. The general small amount of congestion will gradually absorb in 3 to 5 days and the color will become lighter and return to normal. 2. After the blood draw, symptoms such as dizziness, vertigo, fatigue, etc. should be immediately supine, drink a small amount of syrup, and then undergo a physical examination after the symptoms are relieved.