Plasma Dihydrotestosterone (DHT)

Plasma dihydrotestosterone acts as a so-called true androgen on the accessory glands (prostate, seminal vesicles, etc.). A 5α-hydrogenase that forms the sterol is present in the cells of the accessory gonad. The complex in which the sterol and the receptor protein are combined in the cell enters the nucleus of the accessory gland to promote new protein synthesis. Shows a slightly stronger androgenic effect than testosterone. Although 5α-DHT exists in the form of testosterone in the liver, cockscomb, etc., it does not have the action of androgen. 5α-dihydrotestosterone is metabolized to 5α-androstane-3α-17β-diol by the action of 3α-hydroxysterol dehydrogenase. Clinically, radioimmunoassay is commonly used. Basic Information Specialist classification: growth and development examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Found in testicular dysplasia, testicular stromal cell dysplasia. Normal value: DHT (male): 30-85ng/ml DHT (female): 4-22ng/ml Above normal: Found in prostatic hypertrophy, testicular stromal tumor, female hairy and polycystic ovary syndrome. negative: Positive: Tips: Do not eat too greasy, high-protein foods the day before the blood draw, avoid heavy drinking. The alcohol content in the blood directly affects the test results. After 8 pm on the day before the medical examination, you should start fasting for 12 hours to avoid affecting the test results. Normal value Male 1.03 ± 2.92 nmol / L (30 ~ 85 ng / ml). Female 0.14 ± 0.76nmol / L (4 ~ 22ng / ml). Clinical significance (1) elevated in prostate hypertrophy, testicular stromal tumor, female hairy and polycystic ovary syndrome. (2) Reduced in testicular dysplasia, Leydig cells dysplasia. Low results may be diseases: congenital testicular hypoplasia results may be high disease: polycystic ovary syndrome considerations First, the precautions before blood draw 1, do not eat too greasy, high-protein food the day before the blood, to avoid heavy drinking. The alcohol content in the blood directly affects the test results. 2. After 8 pm on the day before the medical examination, you should start fasting for 12 hours to avoid affecting the test results. 3, should relax when taking blood, to avoid the contraction of blood vessels caused by fear, increase the difficulty of blood collection. Second, should pay attention after blood draw 1. After blood is drawn, local compression is required at the pinhole for 3-5 minutes to stop bleeding. Note: Do not rub, so as not to cause subcutaneous hematoma. 2, the pressing time should be sufficient. There is a difference in clotting time for each person, and some people need a little longer to clotting. Therefore, when the surface of the skin appears to be bleeding, the compression is stopped immediately, and the blood may be infiltrated into the skin due to incomplete hemostasis. Therefore, the compression time is longer to completely stop bleeding. If there is a tendency to bleed, the compression time should be extended. 3, after the blood draw symptoms of fainting such as: dizziness, vertigo, fatigue, etc. should immediately lie down, drink a small amount of syrup, and then undergo a physical examination after the symptoms are relieved. 4. If there is localized congestion, use a warm towel after 24 hours to promote absorption. 3. Please inform the doctor about the recent medication and special physiological changes before the test, and pay attention to the doctors to stop taking some foods that may affect the results of hormone determination and drugs such as clomiphene. Inspection process Determination of gonadotropins. Not suitable for the crowd People with reduced hematopoietic function such as leukemia, various anemia, myelodysplastic syndrome, or people with thrombocytopenia should pay attention to blood draw, and should not take more or more blood. Adverse reactions and risks 1. After the blood is drawn, do not press the needle hole to avoid subcutaneous hematoma. If there is a small piece of bruise in the blood, it is slightly tender, please don't panic, you can do hot compress after 24 hours to promote the absorption of blood. The general small amount of congestion will gradually absorb in 3 to 5 days and the color will become lighter and return to normal. 2. After the blood draw, symptoms such as dizziness, vertigo, fatigue, etc. should be immediately supine, drink a small amount of syrup, and then undergo a physical examination after the symptoms are relieved.