Plasma 18-hydroxy-deoxycorticosterone

18-hydroxy-deoxycorticosterone is a 21 carbon steroid hormone. It is mainly produced by the adrenal cortical bundle and is a mineralocorticoid. Its secretion is regulated by ACTH and renin and angiotensin system, the former is the main. Its biological effect is mainly sodium and potassium. Basic Information Specialist classification: Oncology examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Found in Edison, the anterior pituitary function is low. Normal value: Plasma 18-hydroxy-deoxycorticosterone (food): 42-94 ng/L Plasma 18-hydroxy-deoxycutaneous &#: 101-149ng/L Above normal: Found in Cushing's syndrome or Cushing's disease, primary aldosteronism, essential hypertension. negative: Positive: Tips: Due to the physiological fluctuation of cortisol in the blood, it is the highest in the morning, gradually decreases afterwards, and falls to the lowest level after falling asleep. Clinically, blood samples are generally taken at around 8:00 in the morning for examination. Normal value General food (68 ± 26) ng / L. Low sodium diet (125 ± 24) ng / L. High sodium diet (66 ± 8) ng / L. Clinical significance 18-hydroxy-deoxycorticosterone assay can reflect pituitary-adrenal function. Increased plasma 18-OH-DOC is seen in Cushing's syndrome or Cushing's disease, primary aldosteronism, and essential hypertension. Decreased 18-hydroxy-deoxycorticosterone was found in Edison's disease and anterior pituitary function was low. High results may be diseases: Cushing's syndrome, primary aldosteronism, essential hypertension considerations Due to the physiological fluctuation of cortisol in the blood, it is the highest in the morning, and then gradually decreases, and falls to the lowest level after falling asleep. Clinically, blood samples are generally taken at around 8:00 in the morning for examination. Inspection process Antigen to antibody reaction, B and F separation and radioactivity determination. Not suitable for the crowd People with reduced hematopoietic function such as leukemia, various anemia, myelodysplastic syndrome, or people with thrombocytopenia should pay attention to blood draw, and should not take more or more blood. Adverse reactions and risks 1. After the blood is drawn, do not press the needle hole to avoid subcutaneous hematoma. If there is a small piece of bruise in the blood, it is slightly tender, please don't panic, you can do hot compress after 24 hours to promote the absorption of blood. The general small amount of congestion will gradually absorb in 3 to 5 days and the color will become lighter and return to normal. 2. After the blood draw, symptoms such as dizziness, vertigo, fatigue, etc. should be immediately supine, drink a small amount of syrup, and then undergo a physical examination after the symptoms are relieved.