Total gastric acidity determination

Total acidity includes free acids, bound acids, and organic acids derived from food or bacterial metabolism such as lactic acid, vinegar, and acidic phosphates. Basic Information Specialist classification: Digestive examination classification: endocrine examination Applicable gender: whether men and women apply fasting: fasting Tips: Eliminate tension and try to get the stomach juice with your doctor. Normal value The free acid of normal fasting gastric juice is 0-30U, with an average of 18U; the total acidity is 10~50U, with an average of 30U. After taking the test for 1 hour or injecting histamine for 20 minutes, the total acidity gradually reached a peak. The total acidity can reach 50-75 U after the test, and 40-150 U after the injection of histamine. (Note the specific reference value depends on each laboratory.) Clinical significance Increased gastric acid is seen in ulcer disease, high acid gastritis, pyloric obstruction, gastrinoma (secretion of gastric acid is often 3 to 6 times more than normal people). Gastric acid reduction is seen in atrophic gastritis, gastric dilatation, secondary iron deficiency anemia, pernicious anemia, and gastric cancer. In the case of true gastric acid deficiency, gastric acid does not increase after the test meal or injection of histamine, but it is also occasionally seen in the elderly without gastric acidosis. Low results may be diseases: atrophic gastritis, acute gastric dilatation, iron deficiency anemia results may be high disease: gastric ulcer, pyloric obstruction precautions Eliminate tension and try to get your stomach juice with your doctor. Gastric tube collection method: 1. The action should be light when intubating, do not damage the esophageal mucosa. You should be proficient in the depth and method of intubation. 2. If coughing, difficulty breathing, cyanosis, etc. occur during intubation, it is suggested to enter the trachea. It should be pulled out immediately, and then rested after a short break. 3. After insertion, check if the stomach tube is in the stomach by the following method (1) Connect the end of the stomach tube to the syringe. If the gastric juice can be withdrawn, the stomach tube is proved to be in the stomach. (2) Inject 10 ml of air from the stomach tube with a syringe, and use a stethoscope to pick up the gas over water in the stomach, indicating that the stomach tube is in the stomach. (3) Place the open end of the stomach tube under the water surface, and insert the airway into the trachea if the patient escapes when exhaling. Inspection process (1) For each specimen to be tested, first measure the pH value with a pH test paper, and determine the acidity. If the pH is >3, the acid ion concentration is accurately determined by a pH meter. (2) Take 5 ml of clarified gastric juice and add 2 drops of 0.2 g/L phenol red indicator (if it is yellow, it means there is gastric acid). Titrate with 0.1 mol/L NaOH solution until the initial red color (end point pH 7.0), multiply the number of NaOH mL consumed by 20, which is the content of mmol/L per liter of gastric acid concentration (divide by 1000 to be per ml) Gastric acid concentration). Not suitable for the crowd Any esophageal varices, esophageal stenosis, esophageal tumor, aortic aneurysm, severe hypertension, cardiovascular disease, heart failure, late pregnancy, physical weakness and other serious diseases should not be inserted into the stomach tube. Adverse reactions and risks If coughing, difficulty breathing, cyanosis, etc. occur during intubation, it is suggested to enter the trachea. It should be pulled out immediately, and then rested after a short break.