Calcitonin

Calcitonin is a single-chain peptide hormone that is synthesized and secreted by thyroid follicular cells and is mainly metabolized by the kidney. It can reduce the concentration of calcium and phosphorus in plasma, inhibit the absorption of calcium and phosphorus, and is an antagonist of parathyroid hormone. The target organs whose main biological activities are bone and kidney. Generally, the increase and decrease of calcium levels indicate the secretion of calcitonin, and the level of calcium in the circulation increases, and the level of calcitonin also rises rapidly. The clinical significance of measuring calcitonin is mainly to monitor the efficacy and cancer recurrence. Continued elevation of calcitonin levels after all thyroidectomy indicates residual tumor tissue formation. Basic Information Specialist classification: examination classification: endocrine examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Can be seen in thyroid congenital hypoplasia or surgical resection. Normal value: Serum ct (male): 0-14 ng / L Serum ct (female): 0-28ng/L Above normal: Can be seen in malignant tumors and acute and chronic renal insufficiency. negative: Positive: Tips: Do not eat too greasy, high-protein foods the day before the blood draw, avoid heavy drinking. The alcohol content in the blood directly affects the test results. Normal value Male 0 ~ 14ng / L. Female 0 ~ 28ng / L. Clinical significance Elevated in thyroid cancer, small cell lung cancer, breast cancer. Especially in patients with tumor bone metastases, the blood calcitonin content is mostly increased, and calcitonin can reflect the size of the cancer. In addition, kidney failure, pregnant women, and leukemia can also be elevated. High results may be diseases: thyroid cancer, thyroid microcarcinoma, chronic renal insufficiency, Merkel cell carcinoma, acute renal insufficiency Before inspection: 1, do not eat too greasy, high-protein food the day before the blood, to avoid heavy drinking. The alcohol content in the blood directly affects the test results. 2. Fasting for 12 hours before taking blood, taking fresh blood for inspection. When checking: When you take blood, you should relax your mind, avoid the contraction of blood vessels caused by fear, and increase the difficulty of blood collection. After inspection: 1. After blood is drawn, local compression is required at the pinhole for 3-5 minutes to stop bleeding. Note: Do not rub, so as not to cause subcutaneous hematoma. 2, the pressing time should be sufficient. There is a difference in clotting time for each person, and some people need a little longer to clotting. Therefore, when the surface of the skin appears to be bleeding, the compression is stopped immediately, and the blood may be infiltrated into the skin due to incomplete hemostasis. Therefore, the compression time is longer to completely stop bleeding. If there is a tendency to bleed, the compression time should be extended. 3, after the blood draw symptoms of fainting such as: dizziness, vertigo, fatigue, etc. should immediately lie down, drink a small amount of syrup, and then undergo a physical examination after the symptoms are relieved. 4. If there is localized congestion, use a warm towel after 24 hours to promote absorption. Inspection process Blood tests, immunological or chemiluminescence. Not suitable for the crowd Nothing. Adverse reactions and risks Nothing.