Thyroid Binding Globulin (TBG)

Thyroid-binding globulin is a binding carrier of thyroid hormone, which directly affects the total content of serum T3 and T4. Serum thyroid-binding globulin is commonly used to rule out changes in T3 and T4 caused by non-thyroid dysfunction. Further improve the diagnosis rate of thyroid diseases. Basic Information Specialist classification: growth and development check classification: endocrine examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Hyperthyroidism, nephrotic syndrome, cirrhosis, metastatic malignancy, congenital TBG deficiency, androgen therapy, protein-induced enteritis. Normal value: TBG: 15-34mg/L Above normal: Hypothyroidism, pregnancy, estrogen therapy, infectious hepatitis, bone tumors, congenital TBG hyperplasia, acute intermittent porphyria. negative: Positive: Tips: Do not eat too greasy, high-protein food the day before, avoid heavy drinking. The alcohol content in the blood will directly affect the test results. Before the test, fasting for 12 hours, fresh blood is sent for inspection. Normal value The reference value is 15 to 34 mg/L. Clinical significance Abnormal result (1) In addition to hypothyroidism, TBG is also seen in pregnancy, estrogen therapy, infectious hepatitis, bone tumors, congenital TBG hyperplasia, acute intermittent porphyria. (2) In addition to hyperthyroidism, TBG reduction is also seen in: nephrotic syndrome, cirrhosis, metastatic malignancy, congenital TBG deficiency, androgen therapy, protein-induced enteritis. Person who needs to be tested Abnormal liver function, hyperthyroidism, hypothyroidism. Low results may be diseases: congenital hypothyroidism, cirrhosis, nephrotic syndrome in children Before the test: Do not eat too greasy, high-protein food the day before, avoid heavy drinking. The alcohol content in the blood will directly affect the test results. Before the test, fasting for 12 hours, fresh blood is sent for inspection. During the examination: should relax, avoid the contraction of blood vessels caused by fear, and increase the difficulty of blood collection. After the examination: Do not rub, so as not to cause subcutaneous hematoma. Inspection process After blood draw, it is determined by immunological methods. Not suitable for the crowd People with reduced hematopoietic function such as leukemia, various anemia, myelodysplastic syndrome, or people with thrombocytopenia should pay attention to blood draw, and should not take more or more blood. Adverse reactions and risks 1. After the blood is drawn, do not press the needle hole to avoid subcutaneous hematoma. If there is a small piece of bruise in the blood, it is slightly tender, please don't panic, you can do hot compress after 24 hours to promote the absorption of blood. The general small amount of congestion will gradually absorb in 3 to 5 days and the color will become lighter and return to normal. 2. After the blood draw, symptoms such as dizziness, vertigo, fatigue, etc. should be immediately supine, drink a small amount of syrup, and then undergo a physical examination after the symptoms are relieved.