parathyroid hormone

Parathyroid hormone is secreted by the main cells of the parathyroid glands. The parathyroid hormone molecule is a peptide consisting of 84 amino acids. Its physiological role is mainly to increase blood calcium, lower blood phosphorus, and regulate calcium levels. Generally, plasma calcium levels are inversely proportional to plasma parathyroid hormone levels. Determination of parathyroid hormone has a certain value in the identification of hypercalcemia and hypocalcemia, and is important for the diagnosis of parathyroid disease and monitoring of hemodialysis. Basic Information Specialist classification: growth and development check classification: endocrine examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Non-parathyroid hypercalcemia caused by hypoparathyroidism, renal failure, and hyperthyroidism caused by thyroidectomy. Normal value: Amino terminal (radioimmunoassay): 230 ng / L - 630 ng / Lng / L or pmol / L Carboxy terminal (radioimmunoassay): 430 ng / L - 1860 ng / Lng / L or pmol / L Above normal: Primary hyperparathyroidism, ectopic hyperparathyroidism, hyperparathyroidism secondary to nephropathy, pseudohypoparathyroidism. negative: Positive: Tips: Before the inspection, you must stop eating foods rich in iodine, such as kelp, seaweed, sea fish and shrimp, etc., depending on the amount of food, stop eating for 2-4 weeks. Normal value Radioimmunoassay: amino terminal (active end) 230 ~ 630 ng / L; carboxy end (inactive end) 430 ~ 1860 ng / L. Immunochemical fluorescence method: 1 ~ 10pmol / L. Clinical significance Reduced in idiopathic hypoparathyroidism, hypothyroidism after thyroid tumor resection, malignant tumor bone metastasis, severe hypomagnesemia. Elevation is seen in hyperparathyroidism (increased blood calcium, decreased blood phosphorus), and can also be seen in ectopic hyperthyroidism, such as kidney cancer, bronchial cancer. Low results may be diseases: congenital thymic hypoplasia, false hypoparathyroidism, high results may be diseases: primary hyperparathyroidism, hypoparathyroidism, renal failure, primary Hyperparathyroidism and nephropathy, parathyroid bone malnutrition precautions Before inspection: 1. Before the inspection, you must stop eating foods rich in iodine, such as kelp, seaweed, sea fish and shrimp, etc., depending on the amount of food, stop eating for 2 to 4 weeks. 2. The following drugs should be stopped before the examination. According to the dosage and time, stop taking 2~8 weeks. (1), iodine-containing drugs, such as iodide, compound iodine solution, iodine-containing tablets, etc. (2) Drugs that affect thyroid function, such as thyroid tablets and antithyroid drugs. (3) Some Chinese herbal medicines, such as seaweed, kelp, fritillary, burdock, Mutong, etc. When checking: Check that the patient should be fasting on the day. Inspection process A common method for determining serum hormones is radioimmunoassay (RIA). This method combines the sensitivity of radiation with the specificity of the immune response and is a reliable, economical and specific assay. It is not affected by the amount of iodine contained in food; it is harmless to the human body after blood collection, and can be applied to pregnant women, lactating women, newborns and endangered patients; this method takes small blood volume and can be measured in other fields. It can also be repeatedly measured and widely used in clinical practice. Not suitable for the crowd Generally no taboos. Adverse reactions and risks Generally not.