Estrone (E1)

Estrone is mainly synthesized in ovarian granulosa cells in women, and a small amount is derived from the conversion of androstenedione. Male estrone is mainly derived from androstenedione, and a small amount is directly secreted from the testes. The detection of estrone is important for understanding the endocrine function of the ovary and judging whether or not ovulation is effective in women of childbearing age. Women of normal reproductive age showed parallel changes in plasma estrone and estradiol throughout the menstrual cycle. After menopause, estrogen levels decreased and plasma estradiol decreased more than estrone. Basic Information Specialist classification: examination classification: endocrine examination Applicable gender: whether men and women apply fasting: fasting Tips: It is not advisable to have a urine test during a cold. Generally, you can do it after a week. It is also best not to leave urine for diarrhea. Normal value serum Male puberty 41 ~ 78pmol / L; adult 111 ~ 629pmol / L. Female early follicular phase 110 ~ 184pmol / L; late follicular phase 550 ~ 1100pmol / L; luteal phase 404pmol / L; menopause 73 ~ 147pmol / L. Clinical significance Elevation is seen in normal pregnancy (after 12 weeks), liver disease, polycystic ovary syndrome, adrenal or testicular tumors, ovarian granulosa cell tumors, and the like. Reduced in abnormal pregnancy, ovarian dysfunction, amenorrhea, pituitary gonadotropin cell dysfunction, high prolactin syndrome. Low results may be diseases: high amenorrhea results may be diseases: polycystic ovary syndrome considerations Blood specimen: First, the precautions before blood draw 1, do not eat too greasy, high-protein food the day before the blood, to avoid heavy drinking. The alcohol content in the blood directly affects the test results. 2. After 8 pm on the day before the medical examination, you should start fasting for 12 hours to avoid affecting the test results. 3, should relax when taking blood, to avoid the contraction of blood vessels caused by fear, increase the difficulty of blood collection. Second, should pay attention after blood draw 1. After blood is drawn, local compression is required at the pinhole for 3-5 minutes to stop bleeding. Note: Do not rub, so as not to cause subcutaneous hematoma. 2, the pressing time should be sufficient. There is a difference in clotting time for each person, and some people need a little longer to clotting. Therefore, when the surface of the skin appears to be bleeding, the compression is stopped immediately, and the blood may be infiltrated into the skin due to incomplete hemostasis. Therefore, the compression time is longer to completely stop bleeding. If there is a tendency to bleed, the compression time should be extended. 3, after the blood draw symptoms of fainting such as: dizziness, vertigo, fatigue, etc. should immediately lie down, drink a small amount of syrup, and then undergo a physical examination after the symptoms are relieved. 4. If there is localized congestion, use a warm towel after 24 hours to promote absorption. 3. Please inform the doctor about the recent drug use and special physiological changes before the test. Pay attention to avoid taking the drugs that affect the results before the test, and follow the doctor's advice. For 24-hour urine specimens, please note: 1, stay 24 hours of urine on the same day of normal diet, normal activities, do not deliberately drink too much water, neither can stay in bed nor too vigorous exercise 2. When the weather is hot, some hospitals require preservatives to prevent the urine from deteriorating. The first urine collected after emptying the bladder at 7:00 on the first day is added to the container together with the preservative. However, it is best to add nothing, and the collected urine is most scientifically stored in the refrigerator. 3, during the cold period should not be done urine test, generally wait for a cold after a week to do. It is also best not to leave urine for diarrhea. Inspection process Hormone assay. Not suitable for the crowd People with reduced hematopoietic function such as leukemia, various anemia, myelodysplastic syndrome, or people with thrombocytopenia should pay attention to blood draw, and should not take more or more blood. Adverse reactions and risks 1. After the blood is drawn, do not press the needle hole to avoid subcutaneous hematoma. If there is a small piece of bruise in the blood, it is slightly tender, please don't panic, you can do hot compress after 24 hours to promote the absorption of blood. The general small amount of congestion will gradually absorb in 3 to 5 days and the color will become lighter and return to normal. 2. After the blood draw, symptoms such as dizziness, vertigo, fatigue, etc. should be immediately supine, drink a small amount of syrup, and then undergo a physical examination after the symptoms are relieved.