Hepatitis B virus core antibody (HBcAb)

Hepatitis B virus core antibody (HBcAb) is a corresponding antibody against hepatitis B virus core antigen. It is not a protective antibody, and its presence is one of the indicators of hepatitis B virus infection. It includes three types of IgM, IgA, and IgG. IgM type is an important indicator for judging acute hepatitis B. It is the earliest specific antibody in the blood after infection with hepatitis B virus, and it usually lasts for 3-6 months. If the HBcAb-IgM continues to be high titers, it indicates that the patient has a chronic tendency to hepatitis B. If the HBcAb-IgM titer is high in patients with chronic active hepatitis B, it indicates that hepatitis B virus is actively replicating in the body and is one of the indicators of strong contagiousness. HBcAb-IgG appeared later, not a protective antibody, and the detection of HBcAb-IgG has epidemiological significance. Basic Information Specialist classification: Infectious disease examination and classification: blood examination Applicable gender: whether men and women apply fasting: not fasting Analysis results: Below normal: Normal value: no Above normal: negative: normal. Positive: Represented an infection with hepatitis B virus or a hepatitis B virus that has been infected. Tips: If the examiner wants to check liver function (hepatitis B ultrasound) at the same time, it must be fasted. Normal value negative. Clinical significance HBcAb is a marker of infection with hepatitis B virus. Its detection can detect a part of hepatitis B virus infected by HBsAg and HBsAb, and it plays an important role in the diagnosis of hepatitis B. 1. Single HBcAb positive is seen in the early recovery (window period) after acute infection of hepatitis B. It can also be seen in the period when HBsAg disappears and HBsAb has not yet appeared. It can also be seen in infants who transmit hepatitis B virus from the mother through the placenta. 2. HBcAb-IgG positive indicates previous infection with hepatitis B virus. 3. HBcAb-IgM positivity indicates acute or recent infection with hepatitis B virus and viral replication. If the HBcAb-IgM continues to be high titers, it indicates that the patient has a chronic tendency to hepatitis B. If the HBcAb-IgM titer is high in patients with chronic active hepatitis B, it indicates that hepatitis B virus is actively replicating in the body and is one of the indicators of strong contagiousness. 4. Hepatitis B "small three yang" It means that hepatitis B surface antigen (HBsAg), E antibody (HBeAb) and core antibody (HBcAb) are positive in the two-pair test of hepatitis B. prompt (1) In most cases, it indicates a reduction in hepatitis B virus replication. Still contagious. (2) The shift from "big three yang" to "small three yang" does not mean that hepatitis B virus replication completely stops. A small number of "small three yang" patients have positive serum HBV-DNA, active virus replication, serious disease, and rapid progress. Seen in the virus variation. 5. Hepatitis B "Da Sanyang" means that hepatitis B surface antigen (HBsAg), E antigen (HBeAg) and core antibody (HBcAb) are positive in the two-and-a-half test of hepatitis B. It is suggested that hepatitis B virus infection is active and infectious. It does not indicate whether the condition is serious. Positive results may be diseases: acute and chronic hepatitis, chronic hepatitis, cirrhosis The test results must be combined with several other hepatitis B test results. Inspection process 1. Intravenous blood draw, laboratory test. 2. Serological examination of the virus. Not suitable for the crowd People with reduced hematopoietic function such as leukemia, various anemia, myelodysplastic syndrome, or people with thrombocytopenia should pay attention to blood draw, and should not take more or more blood. Adverse reactions and risks 1. After the blood is drawn, do not press the needle hole to avoid subcutaneous hematoma. If there is a small piece of bruise in the blood, it is slightly tender, please don't panic, you can do hot compress after 24 hours to promote the absorption of blood. The general small amount of congestion will gradually absorb in 3 to 5 days and the color will become lighter and return to normal. 2. After the blood draw, symptoms such as dizziness, vertigo, fatigue, etc. should be immediately supine, drink a small amount of syrup, and then undergo a physical examination after the symptoms are relieved.