Serum immunoglobulin assay

The determination of serum immunoglobulin (Ig) is the most common method for examining humoral immune function. Usually, IgG, IgM, and IgA are detected, and these three types of Ig can represent the level of serum Ig. Immunoglobulin (Ig) has antibody activity and can specifically bind to the corresponding antigen, and is a kind of protein ubiquitous in the body. Basic Information Specialist classification: cardiovascular examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Tips: Do not eat too greasy, high-protein foods the day before the blood draw, avoid heavy drinking. The alcohol content in the blood directly affects the test results. After 8 pm on the day before the medical examination, fasting should be done to avoid affecting the detection of indicators such as blood glucose in the second sky. Normal value IgG 7.6 to 16.6 g/L; IgA 0.71 to 3.35 g/L; IgM 0.48 to 2.12 g/L; IgD 0.01 to 0.04 g/L; and IgE 0.001 to 0.009 g/L. Clinical significance Ig significantly reduced 1 found in congenital hypogammaglobulinemia, such as IgG, IgA, IgM three completely lack of Bruton disease (limited to men), three Ig lack of one or two (reduced or incompetent) gamma globulin abnormal blood Symptoms, the latter most commonly seen is IgA deficiency (recessive inheritance). 2 seen in acquired hypogammaglobulinemia (such as nephrotic syndrome, protein-losing enteropathy, congenital rubella, etc.) and Swiss thymic dysplasia with no agammaglobulinemia. Ig is significantly increased 1 seen in immune diseases, such as acute systemic lupus erythematosus, chronic active hepatitis, rheumatoid arthritis active period. 3 found in multiple myeloma, depending on the Ig produced, there are G type (increased IgG), type A (IgA increased), D type, E type (the latter two types are rare). 4 seen in infections, such as chronic suppurative infection, tuberculosis, liver abscess, schistosomiasis, tumor-type leprosy, etc., showing elevated IgG. 5 seen in malignant tumors, such as digestive tract cancer, respiratory cancer, genitourinary cancer, the vast majority of patients see increased IgA. Laryngeal cancer, colon cancer, rectal cancer, and prostate cancer IgM also increased. IgE is seen in allergic diseases and parasitic diseases. High results may be diseases: exogenous allergic alveolitis in children, extracellular cholesterol syndrome in children, precautions for neonatal cytomegalovirus infection First, the precautions before blood draw 1, do not eat too greasy, high-protein food the day before the blood, to avoid heavy drinking. The alcohol content in the blood directly affects the test results. 2. After 8 pm on the day before the physical examination, fasting should be done to avoid affecting the detection of indicators such as blood glucose in the second sky. 3, should relax when taking blood, to avoid the contraction of blood vessels caused by fear, increase the difficulty of blood collection. If you have a history of fainting blood, please explain in advance and make special arrangements. Second, should pay attention after blood draw 1. After blood is drawn, local compression is required at the pinhole for 3-5 minutes to stop bleeding. Note: Do not rub, so as not to cause subcutaneous hematoma. 2, the pressing time should be sufficient. There is a difference in clotting time for each person, and some people need a little longer to clotting. Therefore, when the surface of the skin appears to be bleeding, the compression is stopped immediately, and the blood may be infiltrated into the skin due to incomplete hemostasis. Therefore, the compression time is longer to completely stop bleeding. If there is a tendency to bleed, the compression time should be extended. 3, after the blood draw symptoms of dizziness, such as: dizziness, vertigo, fatigue, etc. should immediately lie down, drink a small amount of sugar water, and then undergo a physical examination after the symptoms are relieved. 4. If there is localized congestion, use a warm towel after 24 hours to promote absorption. Inspection process Serum protein acetate membrane electrophoresis. Not suitable for the crowd There are no special taboos. Adverse reactions and risks No related complications and hazards.