Serum immunoglobulin G (IgG)

Immunoglobulin G (IgG) is synthesized in the spleen and lymph nodes, is the highest in human serum (75% of Ig), and has a long half-life in serum, mainly distributed in serum and tissue fluid, and is antibacterial, The main component of anti-toxin and anti-viral antibodies is also an important material basis for the body's anti-infective immunity process. Because IgG is the highest content, it is the most important material basis for human immune response, and it is also the only immunoglobulin that can pass through the placental barrier. It plays an important role in mammalian newborn pups and neonatal anti-infection. So it is often mentioned that immunoglobulins are all about IgG. Basic Information Specialist classification: cardiovascular examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Tips: Do not eat too greasy, high-protein foods the day before the blood draw, avoid heavy drinking. The alcohol content in the blood directly affects the test results. After 8 pm on the day before the medical examination, you should start fasting for 12 hours to avoid affecting the test results. Normal value Immunoturbidimetric method The umbilical cord is 7.6 to 17 g/L (760 to 1700 mg/dl). Neonates 7 to 14.8 g/L (700 to 1480 mg/dl). 0.5 to 6 months 3 to 10 g/L (300 to 1000 mg/dl). 6 months to 2 years old 5 ~ 12g / L (500 ~ 1200mg / dl). 2 to 6 years old 5 to 13 g / L (500 ~ 1300 mg / dl). 6 to 12 years old 7 to 16.5 g / L (700 ~ 1650 mg / dl). 12 to 16 years old 7 to 15.5 g / L (700 ~ 1550 mg / dl). Adult 6 ~ 16g / L (600 ~ 1600mg / dl). (Note the specific reference value depends on each laboratory.) Clinical significance (1) rise 1 connective tissue disease systemic lupus erythematosus, rheumatoid arthritis, scleroderma, Sjögren syndrome (Sjogren's syndrome, Sjogren's syndrome) and the like. 2 IgG type multiple myeloma, primary monoclonal gamma globulinemia. 3 liver disease chronic viral active hepatitis, concealed cirrhosis, lupus-like hepatitis and the like. 4 infectious diseases tuberculosis, leprosy, kala-azar, infectious mononucleosis, sexually transmitted diseases, lymphogranuloma, radiation sickness malaria, trypanosomiasis, etc. 5 types of sarcoma. 6 other Hodgkin's disease, monocytic leukemia, Behcet's disease, nephritis, allergic purpura and so on. (2) lower Non-IgG type dopa's myeloma, heavy chain disease, light chain disease, nephrotic syndrome, malignant lymphoma, chronic lymphocytic leukemia, primary non-gammaglobulinemia, secondary immunodeficiency disease (using immunosuppression) Agents such as cyclophosphamide, corticosteroids, radiation, etc.). High results may be diseases: pediatric hepatitis E, thrombocytopenic purpura after transfusion, selective immunoglobulin A deficiency in children, acute transverse myelitis in children, vascular immunoblastic lymphadenopathy in children, juvenile rheumatoid disease , primary immunodeficiency disease, severe combined immunodeficiency disease, multiple transient white spot syndrome First, the precautions before blood draw 1, do not eat too greasy, high-protein food the day before the blood, to avoid heavy drinking. The alcohol content in the blood directly affects the test results. 2. After 8 pm on the day before the medical examination, you should start fasting for 12 hours to avoid affecting the test results. 3, should relax when taking blood, to avoid the contraction of blood vessels caused by fear, increase the difficulty of blood collection. Second, should pay attention after blood draw 1. After blood is drawn, local compression is required at the pinhole for 3-5 minutes to stop bleeding. Note: Do not rub, so as not to cause subcutaneous hematoma. 2, the pressing time should be sufficient. There is a difference in clotting time for each person, and some people need a little longer to clotting. Therefore, when the surface of the skin appears to be bleeding, the compression is stopped immediately, and the blood may be infiltrated into the skin due to incomplete hemostasis. Therefore, the compression time is longer to completely stop bleeding. If there is a tendency to bleed, the compression time should be extended. 3, after the blood draw symptoms of fainting such as: dizziness, vertigo, fatigue, etc. should immediately lie down, drink a small amount of syrup, and then undergo a physical examination after the symptoms are relieved. 4. If there is localized congestion, use a warm towel after 24 hours to promote absorption. Inspection process One-way immunodiffusion method. Not suitable for the crowd There are no special taboos. Adverse reactions and risks No relevant records.