Lymphocyte transformation rate

There are many receptors on the surface of T lymphocytes. Under the stimulation of adding specific antigen or non-specific mitogen in vitro, a series of changes can be made in cell metabolism and morphology, such as transformation into bulky protolymphocytes. The number of transformed cells can reflect the cellular immune function of the body, determine the response ability of T lymphocytes, and diagnose cellular immunodeficiency diseases. The traditional method for detecting lymphocyte transformation rate is to culture whole blood or isolated lymphocytes together with mitogen for a certain period of time, and observe the proportion of lymphocytes transformed into mother cells, thereby determining the lymphocyte transformation rate. Basic Information Specialist classification: Oncology examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Tips: Do not wear clothes that are too small or too tight, so as to avoid the sleeves being too tight when blood is drawn or the sleeves are too tight after blood drawing, causing blood vessels in the arms. Normal value 0.60 to 0.75. (morphological method) Clinical significance Abnormal results are common in malignant tumors, lymphogranuloma, severe tuberculosis, severe fungal infections, lepromatous leprosy, dystrophic telangiectasia, Hodgkin's disease, chronic lymphocytic leukemia, radiotherapy or immunosuppression using corticosteroids Agents, etc. Elevation is seen in Turner syndrome, acute lymphocytic leukemia, and the like. People in the population who have suspected of the above conditions need to be examined. High results may be diseases: pediatric nodular panniculitis, myocarditis, pediatric Caschin-Beck disease, pediatric facial erythema dwarf syndrome precautions Inappropriate people: generally no special population. Taboo before the examination: It is necessary to cooperate with the doctor to write the correct name, neat and tidy, to avoid confusion caused by the same name or similar names. With these in mind, blood draws are more convenient and faster, and you can better save yourself time for diagnosis. Requirements for inspection: Do not wear clothes that are too small or too tight in cuffs to avoid the sleeves being too tight when blood is drawn or the sleeves are too tight after blood drawing, causing blood vessels in the arms. Different laboratory items should be asked by the doctor and treated differently. Inspection process The traditional method for detecting lymphocyte transformation rate is to culture whole blood or isolated lymphocytes together with mitogen for a certain period of time, and observe the proportion of lymphocytes transformed into mother cells, thereby determining the lymphocyte transformation rate. Not suitable for the crowd There are no special taboos. Adverse reactions and risks There are no related complications and hazards.