Streptomycin intradermal test

An intradermal test is required prior to injection of streptomycin to prevent an allergic reaction at the time of injection. The adverse reactions of streptomycin have toxic reactions in addition to allergic reactions, and are also prone to anaphylactic shock. The incidence is second only to penicillin, but the mortality rate is higher than that of penicillin. The cause is high-sensitivity and other than allergic factors. Related to poisoning factors. Therefore, it should be taken seriously. Basic Information Specialist classification: skin examination classification: immune examination Applicable gender: whether men and women apply fasting: not fasting Tips: If you have a history of allergies to this class of drugs, you should inform in advance to avoid allergic reactions. Normal value negative. Clinical significance Abnormal results Streptomycin skin test false positive rate is higher. Skin tests may be false positives. In order to accurately judge the results, it is best to use a 0.1 ml saline solution in the middle of the right forearm volar for intradermal injection as a control test. 1. Allergic reaction with penicillin, but less common. 2. With systemic numbness, muscle weakness, convulsions, dizziness, tinnitus, deafness and other toxic reactions. The mechanism of allergic reaction to chain toxin is the toxic effect of the drug itself and the impurities containing streptomycin and di-chain plum amine. It has the effect of releasing histamine, dilating arterioles and capillaries, lowering blood pressure, shock; streptomycin and Ca2+ combined, resulting in lower blood calcium, patients with numbness, dizziness, convulsions, initially only numbness of the mouth, severe cases of limbs, face, scalp and other body numbness, and even extremities twitch; block nerve, muscle joints, respiratory depression can occur The limbs are weak; the influence on the eighth pair of cranial nerves causes dizziness, tinnitus, deafness, etc., which are mostly progressive or permanent. People who need to check for the first injection of streptomycin are needed. Positive result may be disease: anaphylactic shock precautions Contraindications before examination: If you have a history of allergies to this type of drug, you should inform in advance to avoid allergic reactions. Requirements for examination: If the child is checked, take care of the child and cooperate with the doctor. Inspection process experiment method: The streptomycin test was taken in 0.1 ml (containing 250 u) for intradermal injection, and the results were judged after 20 minutes. First aid measures for allergic reactions. 1. Same as penicillin. 2. When twitching, give 10% calcium gluconate 10ml intravenously, and reduce the amount as appropriate. 3. Muscle weakness, difficulty breathing, according to the doctor's advice to give Xinsi Ming 0.5 ~ 1mg subcutaneous injection, if necessary, 0.25mg intravenous injection. Not suitable for the crowd Inappropriate people: Children reduce their discretion. Adverse reactions and risks There are no related complications and hazards.