tear-secreting immunoglobulin A

SIgA is a dimer containing a secretory sheet and a J-chain. It is present in colostrum and mucosal secretions such as tears, saliva, gastrointestinal tract and respiratory secretions. It is secreted by the plasma cells in the mucosa to provide the body against microbial invasion. The first line of defense, together with lysozyme and lactoferrin, plays a role in local humoral immunity of ocular tissues. In view of the small amount of tear secretion, the conjunctiva can be stimulated by mechanical methods or chemicals to increase the secretion of tears, so that the amount of specimens and some substances produced by lacrimal glands are increased, which facilitates the analysis of tears; however, the stimulation increases the secretion of tears, which is bound to cause tears. The dilution of certain ingredients is difficult to control the degree of dilution. Therefore, special capillary or filter paper sampling methods are currently used to collect non-stimulated specimens. Basic Information Specialist Category: Ophthalmic Examination Category: Blood Examination Applicable gender: whether men and women apply fasting: fasting Tips: Don't watch TV shows, operate computers and play video games for a long time. Normal value 150 ~ 550mg / L. Clinical significance In patients with herpetic keratitis (HSK), SIgA is significantly reduced, and local ocular surface infections such as chronic conjunctivitis and trachoma are reduced, and SIgA levels are also reduced. Precautions Taboo before inspection: 1. Don't watch TV shows, operate computers and play video games for a long time. 2. Take care to prevent eye trauma. Foreign objects should be treated in the correct way. 3. Rub your eyes without rubbing your hands with a dirty handkerchief or a dirty towel. Do not share bath towels, washbasins, etc. with others. 4. Do not look directly at the sun (especially at noon) and weld light to avoid burning your eyes. 5. In case of eye disease, it is necessary to treat it promptly, and at the same time, be careful not to transmit the bacteria to others. Requirements for examination: IgA cannot pass through the placenta, so newborn babies are susceptible to respiratory and intestinal infections. IgA was synthesized 4 to 6 months after hemorrhage, and gradually increased afterwards, reaching a human level in adolescence. Inspection process In view of the small amount of tear secretion, the conjunctiva can be stimulated by mechanical methods or chemicals to increase the secretion of tears, so that the amount of specimens and some substances produced by lacrimal glands are increased, which facilitates the analysis of tears; however, the stimulation increases the secretion of tears, which is bound to cause tears. The dilution of certain ingredients is difficult to control the degree of dilution. Therefore, special capillary or filter paper sampling methods are currently used to collect non-stimulated specimens. Not suitable for the crowd Inappropriate crowd: baby. Adverse reactions and risks There are no related complications and hazards.