Anti-Histocompatibility Antigen-DR Antibody

Specific receptors on T lymphocytes or immunoglobulins released by B lymphocytes, the glycoproteins of these major histocompatibility complexes (MHC) are of great interest. These proteins are encoded by the short arm of chromosome 6. They are present on the cell surface and in body fluids. In humans, it was first described by J. Dausset in 1958 and is called "transplant antigen." The term "antigen" is used because they have been defined serologically. If the method used for typing is not known, HLA (Human Leukocyte Antigen) specificity, HLA determinant, HLA type, and the like can be used. The term HLA allele can only be used when sequencing or using similar high resolution techniques. The anti-tissue-compatible antigen-DR antibody is a specific antibody against systemic lupus erythematosus and is useful for the diagnosis of systemic lupus erythematosus. It is commonly used in the Raji cell immunoenzyme inhibition assay. Basic Information Specialist classification: examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Normal value: no Above normal: negative: normal. Positive: Systemic lupus erythematosus. Tips: Do not wear clothes that are too small or too tight, so as to avoid the sleeves being too tight when blood is drawn or the sleeves are too tight after blood drawing, causing blood vessels in the arms. Normal value Raji cell immunoenzyme inhibition was negative. Clinical significance Positive systemic lupus erythematosus. Precautions Inappropriate people: generally no special population. Taboo before the examination: It is necessary to cooperate with the doctor to write the correct name, neat and tidy, to avoid confusion caused by the same name or similar names. With these in mind, blood draws are more convenient and faster, and you can better save yourself time for diagnosis. Requirements for inspection: Do not wear clothes that are too small or too tight in cuffs to avoid the sleeves being too tight when blood is drawn or the sleeves are too tight after blood drawing, causing blood vessels in the arms. Different laboratory items should be asked by the doctor and treated differently. Inspection process Raji cell surface has the characteristic of expressing histocompatibility antigen DR (HLA-DR), and the anti-HLA-DR antibody in the tested serum competes with anti-human HLA-DR monoclonal antibody (McAb) to bind to Raji cell surface HLA-DR antigen. To characterize the Raji cell immunoenzyme inhibition assay for the detection of serum anti-HLA-DR antibodies. Not suitable for the crowd There are no special taboos. Adverse reactions and risks There are no related complications and hazards.