anti-lymphocyte antibodies

Among anti-lymphocyte antibodies, cold-reactive IgM-type antibodies are cytotoxic, while IgG-type antibodies are capable of altering lymphocyte function in vitro. Anti-lymphocyte antibodies can affect immune function in a number of ways: 1 Eliminate circulating lymphocytes in the target. 2 binds to the target cell surface antigen to change its function. 3 Eliminate the effect of T suppressor cells. 4 exerts a specific cytotoxic effect on the T cell subsets necessary for the production of T suppressor cells. Basic Information Specialist classification: growth and development check classification: immunological examination Applicable gender: whether men and women apply fasting: not fasting Analysis results: Below normal: Normal value: no Above normal: negative: normal. Positive: Positive indicates systemic lupus erythematosus (SLE). Tips: Do not eat too greasy, high-protein foods the day before the blood draw, avoid heavy drinking. After 8 pm on the day before the medical examination, you should start fasting for 12 hours to avoid affecting the test results. Normal value negative. Clinical significance 86.9% of patients with SLE had ALA in the active blood and reduced the number of lymphocytes (1.5 ± 0.6) × 109 / L. The cells are swollen, the membrane is rough, and the refractive index is lost. Peripheral T lymphocytes in ALA-positive patients were 25% lower than those in ALA-negative patients. ALA in serum was mainly related to changes in the number of T lymphocytes. It is also one of the causes of immune dysfunction. Thus, once ALA is present, the number of inhibitory T cells is reduced and the functions of helper T cells and B cells are relatively enhanced, and a large amount of autoantibodies are produced, resulting in multiple system damage. Hormone therapy can cause ALA to turn negative in most patients with SLE, and the number and morphology of lymphocytes return to normal. Precautions First, the precautions before blood draw: 1, do not eat too greasy, high-protein food the day before the blood, to avoid heavy drinking. The alcohol content in the blood directly affects the test results. 2. After 8 pm on the day before the medical examination, you should start fasting for 12 hours to avoid affecting the test results. 3, should relax when taking blood, to avoid the contraction of blood vessels caused by fear, increase the difficulty of blood collection. Second, after blood draw should pay attention to: 1. After blood is drawn, local compression is required at the pinhole for 3-5 minutes to stop bleeding. Note: Do not rub, so as not to cause subcutaneous hematoma. 2, the pressing time should be sufficient. There is a difference in clotting time for each person, and some people need a little longer to clotting. Therefore, when the surface of the skin appears to be bleeding, the compression is stopped immediately, and the blood may be infiltrated into the skin due to incomplete hemostasis. Therefore, the compression time is longer to completely stop bleeding. If there is a tendency to bleed, the compression time should be extended. 3, after the blood draw symptoms of fainting such as: dizziness, vertigo, fatigue, etc. should immediately lie down, drink a small amount of syrup, and then undergo a physical examination after the symptoms are relieved. 4. If there is localized congestion, use a warm towel after 24 hours to promote absorption. Third, attention: pregnancy, blood transfusion, organ transplantation and other conditions are also induced. 4. Please inform the doctor about the recent medication and special physiological changes before the test. Inspection process Same as the micro-lymphocyte method. Not suitable for the crowd There are no taboos. Adverse reactions and risks There are no related complications and hazards.