anti-keratin antibody

In addition to RF and anti-collagen antibodies, RA patients often contain a variety of other autoantibodies in their serum, and anti-keratin antibodies are relatively specific for the diagnosis of RA. Basic Information Specialist classification: growth and development check classification: immunological examination Applicable gender: whether men and women apply fasting: not fasting Analysis results: Below normal: Normal value: no Above normal: negative: normal. Positive: Abnormal results. Tips: When you draw blood, you should relax your mind and avoid the contraction of blood vessels caused by fear. Normal value negative. Clinical significance In 1979 Young et al reported the diagnostic specificity of the stratum corneum antibody against the rat esophageal epithelium for RA. IgG-type anti-keratin antibodies are present in 36% to 60% of patients' serum, with specificity up to 95%. The pathogenic role of this antibody is not known. With the widespread use of the clinic, it has been found that AKA-positive "healthy people" almost all develop into typical RA. Therefore, AKA can be considered as an early diagnostic indicator of RA. Precautions First, the precautions before blood draw: 1, do not eat too greasy, high-protein food the day before the blood, to avoid heavy drinking. The alcohol content in the blood directly affects the test results. 2. After 8 pm on the day before the medical examination, you should start fasting for 12 hours to avoid affecting the test results. 3, should relax when taking blood, to avoid the contraction of blood vessels caused by fear, increase the difficulty of blood collection. Second, after blood draw should pay attention to: 1. After blood is drawn, local compression is required at the pinhole for 3-5 minutes to stop bleeding. Note: Do not rub, so as not to cause subcutaneous hematoma. 2, the pressing time should be sufficient. There is a difference in clotting time for each person, and some people need a little longer to clotting. Therefore, when the surface of the skin appears to be bleeding, the compression is stopped immediately, and the blood may be infiltrated into the skin due to incomplete hemostasis. Therefore, the compression time is longer to completely stop bleeding. If there is a tendency to bleed, the compression time should be extended. 3, after the blood draw symptoms of fainting such as: dizziness, vertigo, fatigue, etc. should immediately lie down, drink a small amount of syrup, and then undergo a physical examination after the symptoms are relieved. 4. If there is localized congestion, use a warm towel after 24 hours to promote absorption. 3. Please inform the doctor about the recent medication and special physiological changes before the test. Inspection process Same as ELISA. Not suitable for the crowd There are no taboos. Adverse reactions and risks There are no related complications and hazards.