Anti-nucleolar ribonucleic acid (RNA) antibodies

The nucleus contains three RNA polymerase protein polymers (RNA polymerases I, II and III) responsible for transcription of different RNAs. Each complex consists of several subunits, some containing the same RNA polymerase component. Autoantibodies exist in all three anti-RNA polymerases. These antibodies are often presented together in the same patient's serum. Anti-RNA antibodies can only be tested in some conditional laboratory tests, and the difficulty in detection leads to a difference in positive rate, clinical sensitivity and specificity. Basic Information Specialist classification: growth and development check classification: immunological examination Applicable gender: whether men and women apply fasting: not fasting Analysis results: Below normal: Normal value: no Above normal: negative: normal. Positive: Positive systemic scleroderma is 54%, systemic lupus erythematosus is 26%, other connective tissue diseases Tips: The difference between clinical sensitivity and specificity. Normal value negative. Clinical significance Positive systemic scleroderma was 54%, systemic lupus erythematosus was 26%, and other connective tissue diseases were <10%. Some literatures have pointed out that patients with positive anti-RNA antibodies have severe scleroderma on their surface, often involving internal organs such as heart and kidney. Precautions Anti-RNA antibodies can only be tested in some conditional laboratory tests, and the difficulty in detection leads to a difference in positive rate, clinical sensitivity and specificity. Inspection process The protein is considered as an antibody, and the characteristics of the antibody to specifically bind thereto are used for the study. This technology can be used to separate and concentrate specific proteins from samples containing thousands of different proteins. When performing immunoprecipitation, the antibody needs to bind to a substrate. Not suitable for the crowd There are no taboos. Adverse reactions and risks There are no related complications and hazards.