Tuberculin intradermal test

The tuberculin intradermal test refers to the anti-streptolysin "O" test, abbreviated as "O", and is an antibody produced by the body using streptococcal O as an antigen. By measuring the ASO antibody titer in serum, it can be judged whether the patient has a group A hemolytic streptococcus infection, and can be used as one of the auxiliary diagnostic methods for group A hemolytic streptococcal infectious diseases. However, this test has no specific significance, because group A streptococcus infection can cause a variety of human diseases, such as streptococcal infection caused by corresponding tonsillitis, scarlet fever, acute nephritis, subacute bacterial endocarditis, nephrotic syndrome Etc. can cause ASO to rise. After human infection with hemolytic streptococcus, a variety of antibodies can be present in the serum, such as anti-streptokinase antibodies, anti-hyaluronic acid antibodies and anti-"O" hemolysin antibodies, while anti-"O" hemolysin antibodies are active in detecting rheumatism. A serological diagnostic test is more meaningful. ASO is elevated in 60% to 80% of patients with active rheumatism, and multiple tests are normal to help eliminate rheumatism. Basic Information Specialist classification: infectious disease inspection and inspection classification: other inspection Applicable gender: whether men and women apply fasting: not fasting Analysis results: Below normal: Normal value: no Above normal: negative: normal. Positive: Prompt for tuberculosis infection. Tips: When you check, you should relax and eliminate anxiety and anxiety. Normal value No reaction was negative. <4mm suspicious positive. 5 to 10 mm positive (+). 11 to 20 mm positive (++). >20mm positive (+++). Blisters or ulceration positive (++++) or strong positive. Clinical significance Abnormal results: (1) The greater the local response of the OT skin test, the stronger the cellular immune function of the body. Normal people respond positive + ~ ++, strong positive suggestive of active tuberculosis. (2) Negative OT skin test indicates: 1 has not been exposed to M. tuberculosis, generally seen in young children or rural adolescents. BCG can be given 3 to 4 weeks after inoculation, and then re-examined, often turned positive. 2 critical illness, low cellular immune function such as advanced tumor, severe tuberculosis, measles, whooping cough, blush fever, infectious mononucleosis and other acute or active viral or bacterial infections. 3 iatrogenic, such as radiation therapy, high-dose chemotherapy, hormone drugs have significant inhibition of cell and humoral immunity. People who need to be tested: A person who has fever, long-term cough, cough, and itching. Precautions Before inspection: Skin tests must be diluted to the appropriate concentration to avoid causing systemic reactions or exacerbating local reactions. When checking: Relax and unwind your anxiety and anxiety. Inspection process 1 Preparation of skin test solution Take pure tuberculin 0.5ml plus normal saline 4.5ml as the first solution, the dilution is 1:10. Prepare the second, third and fourth solutions according to the above method. 2 skin test methods and results observation. Select 6.6 cm on the flexion joint of the forearm, and inject 0.1 ml of tuberculin solution intradermally into a ridge. Usually starting from 1:1000, if there is no counter-test, large collections should be available in larger concentrations. Finally, to determine whether the child has tuberculosis infection, a 1:100 concentration test is required. If the child has blister conjunctivitis, skin nodular erythema or pleural effusion, it should start at 1:10000. The reaction intensity was observed at 48 to 72 hours after the injection and indicated by the (+) sign. Negative: no redness and induration diameter not exceeding 0.5 cm or only redness without induration. Suspicious: (t) redness and induration diameter below 0.scm. Positive: (+) redness and induration diameter 0.5-0.gcm. (++) redness and knot diameter 1-1.gcm. (+++) redness and induration diameter above ZCin. (++++) There are blisters or necrosis in addition to redness and induration. 3 Precautions 巳 The diluted tuberculin solution can be stored in the refrigerator for 6 weeks. Can not be used if precipitation or yellowing occurs. Not suitable for the crowd There are active tuberculosis patients. Adverse reactions and risks There are no related complications and hazards.