cerebral blood perfusion tomography

Cerebral blood flow perfusion imaging, intravenous injection of small, uncharged and fat-soluble imaging agents that can enter brain cells through the normal blood-brain barrier and subsequently convert to water-soluble substances by hydrolase or lipolytic enzymes. Or decomposed into charged secondary products by reduced glutathione, thereby remaining in the brain tissue; the amount of imaging agent entering the brain cells is positively correlated with the amount of regional cerebral blood flow (rCBF). Since rCBF is generally parallel to local brain function metabolism, this test can also reflect local brain function status to a certain extent. Basic Information Specialist Category: Inspection Category: CT Applicable gender: whether men and women apply fasting: not fasting Tips: Stop taking sedatives, stimulants and other drugs that act on the nervous system 24 hours before the test to avoid the formation of illusions during the examination and affect the judgment of the test results. The examination must be carried out within 3 hours after the meal. Normal value The tomographic imaging was normal, and the images of the three transverse planes of the transverse, coronal, and sagittal planes showed no lesions. Clinical significance Abnormal results: 1. It is valuable for early diagnosis, efficacy evaluation and prognosis of transient ischemic attack and reversible ischemic encephalopathy. Interventional tests such as acetazolamide and dipyridamole can significantly improve sensitivity and contribute to the detection rate of chronic hypoperfused lesions. 2. For the diagnosis of cerebral infarction. Symptoms of cross-cleft brain loss, hyperperfusion, etc. can be found. For clinical symptoms that cannot be explained by CT and MRI, this method can be used to observe whether there is abnormal area of ​​cerebral blood flow outside the lesion. The rate of detection of lacunar infarction is low. 3. Location diagnosis of epileptic foci. The detection rate of epileptic foci is higher, and the detection of seizures by means of Methomemia can further improve the detection rate of lesions. 4. Diagnosis and differential diagnosis of Alzheimer's disease (AD). The extent and extent of regional cerebral blood flow reduction is related to the severity of AD. 5. Evaluate cerebral blood perfusion and function after craniocerebral injury or after surgery. 6, evaluation of brain tumor perfusion, brain tumor surgery and differential diagnosis of recurrence and necrosis after radiotherapy, pro-tumor SPECT imaging and PET imaging, especially PET imaging is more valuable. 7, combined with a variety of physiological load tests to help the study of brain function. 8. Emotional disorders include anxiety, depression, phobia, obsessive-compulsive disorder, functional impairment of schizophrenia, and assisted diagnosis. The people in need of examination have patients with cerebral ischemic diseases and epilepsy. Precautions Pre-examination contraindications: Stop taking sedatives, stimulants and other drugs that act on the nervous system 24 hours before the test to avoid the formation of illusions during the examination and affect the judgment of the test results. Oral potassium chlorate 400mg was taken 30 minutes before the examination to close the choroid plexus; 10 minutes before the injection of the imaging agent, black eye mask and earplugs should be worn until 10 minutes after injection to remove, and the eyes were closed and quietly rested before imaging. Requirements for inspection: The examination must be carried out within 3 hours after the meal. If you cannot eat before the examination, you should follow the doctor's instructions, orally take 50 grams of powdered sugar or 40 ml of 50% glucose intravenously to prevent hypoglycemia. The result of the inspection. The head cannot be moved during the inspection to ensure the authenticity of the image. Inspection process Oral administration of potassium perchlorate 400 mg on an empty stomach to block the thyroid, choroid plexus and nasal mucosa. After 30 minutes, the subject closed the eyes with a black eye mask, and the ear canal was used to plug the external auditory canal. After 5 minutes, the imaging agent was injected intravenously (usually 99mTc-ECD, 740-1110MBq (20-30 mCi)), and the tomographic display was performed 20 minutes later. image. Intervention tests are performed as necessary to improve diagnostic sensitivity. Not suitable for the crowd Inappropriate population: Patients who are allergic to potassium perchlorate.