Hematoporphyrin inhalation test

The hematoporphyrin atomization inhalation test is carried out by the following principle. After inhalation with hemoporphyrin derivative (Hpd for short), the inner layer of the trachea and bronchi can be exposed to different degrees of fluorescence, combined with fiberoptic bronchoscopy. Can improve the detection rate and location diagnosis of lung cancer. After inhaling the salbutamol aerosol, the subject coughed up the respiratory secretions, and then inhaled 10% Hpd solution, the amount of nebulization 11ml-15ml (11-15mg), an average of 14ml. 嘱 深 deep breathing, frequency 8 times / min-24 times / min, an average of 15 times / min-17 times / min. Basic Information Specialist classification: Oncology examination classification: pulmonary function test Applicable gender: whether men and women apply fasting: not fasting Tips: Pay attention to normal eating habits and pay attention to personal hygiene. Those who are allergic to hematoporphyrin, severe heart and lung dysfunction, liver and kidney dysfunction are not suitable for this examination. Normal value No Information. Clinical significance Abnormal results test positive, suggesting lung cancer or suspected lung cancer. Due to the sometimes false positives in fluorescence diagnosis, biopsy is needed for further confirmation. People who need to be examined for lung cancer or suspected lung cancer. Precautions Forbidden before examination: Pay attention to normal eating habits and pay attention to personal hygiene. Requirements for inspection: Actively cooperate with the doctor. Inspection process 1. Prepare the test, perform routine fiberoptic bronchoscopy, and perform a hematoporphyrin allergy test on the subject. 2. After inhaling the salbutamol aerosol, the subject coughed up the respiratory secretions, and then inhaled 10% Hpd solution, the amount of nebulization 11ml-15ml (11-15mg), an average of 14ml. 嘱 深 deep breathing, frequency 8 times / min-24 times / min, an average of 15 times / min-17 times / min. 3. After inhalation of Hpd 5h-6.5h (average 5.8h), first absorb respiratory secretions under normal light to observe whether there are lesions, parts and extent. An argon laser was used to observe the presence of fluorescence, fluorescence intensity, and boundaries with surrounding tissues in the lesion and other parts of the bronchial tree to distinguish true wall fluorescence from secretion fluorescence. Record observations and photographs. 4. Perform a brush examination and/or a biopsy on the fluorescent site (including the upper part of the tumor and the abnormal part of the normal light observation) for pathological examination. RESULTS: The true wall fluorescence (small, spotted, or reticulated) was observed in the lesion by argon laser. Most of the secretion fluorescence is long band. Not suitable for the crowd Inappropriate crowd: 1. Allergic to blood porphyrin. 2. Severe heart and lung dysfunction, liver and kidney dysfunction.