HLA stereotyping

HLA, the human leukocyte antigen (Humanleucocyteantigen), is a human histocompatibility system. This is a group of antigens widely distributed on the surface of human nucleated cells, controlled by the short arm of human chromosome 6. There are at least five HLA gene loci, namely HLA-A, B, C, D and DR sites. In recent years, two sites of DP and DQ have been identified. HLA is highly polymorphic with at least two alleles per locus. Therefore, a range of antigen specificities determined by a single locus can be identified in the population. Therefore, in clinical organ transplantation, in addition to identical twins, donors and recipients should be subjected to strict HLA typing in addition to ABO blood type to select individuals with the same or similar HLA. Basic Information Specialist classification: growth and development check classification: immunological examination Applicable gender: whether men and women apply fasting: not fasting Tips: Clinical organ transplantation, in addition to identical twins, donors and recipients in addition to ABO blood type matching, also need to carry out strict HLA stereotypes to select individuals with the same or similar HLA. Normal value The number of negative blue dead cells was <20%. Clinical significance Tissue or organ transplant matching selects a suitable donor for HLA. Precautions In clinical organ transplantation, in addition to identical twins, donors and recipients should be subjected to strict HLA typing in addition to ABO blood type to select individuals with the same or similar HLA. Inspection process Same as serological assay. Not suitable for the crowd There are no taboos. Adverse reactions and risks There are no related complications and hazards.