Prostatic acid phosphatase (PAP)

Prostatic acid phosphatase (PAP) is a glycoprotein (molecular weight 100,000) synthesized and secreted by mature prostate epithelial cells, which enters the seminal vesicle through the prostate duct and is excreted by the urethra. In prostate cancer, prostate acid phosphatase produced by cancer cells is directly absorbed into the blood circulation due to the destruction of cancer cells by a ductless or glandular duct, resulting in an increase in serum prostatic acid phosphatase. Basic Information Specialist classification: male examination inspection classification: biochemical examination Applicable gender: whether the male is fasting: fasting Tips: When the prostate has acute inflammation, it is contraindicated for prostate massage examination. Normal value Modified solid phase immunoenzymatic method: <1.6 μg/L (serum). Clinical significance This method can be used as a diagnosis, treatment effect and prognosis evaluation of prostate cancer and differential diagnosis of metastatic bone tumor. It is reported that prostate cancer phosphatase is elevated in prostate cancer patients with bone metastases accounted for 80%. Serum prostatic acid phosphatase can be elevated in some patients with benign prostatic hyperplasia. At this time, clinical judgment and follow-up observation should be made. Recent prostate digital rectal examination can cause elevated serum prostatic acid phosphatase, so it is advisable to take blood samples before or 2 weeks after the test. Specimen should not be hemolyzed, otherwise the measurement results may be abnormal. High results may be diseases: prostate cancer, benign prostatic hyperplasia, elderly prostate cancer precautions Note before inspection: 1. When the prostate has acute inflammation, it is contraindicated for prostate massage examination. 2, the force should be even when massage, avoid using violence, so as not to cause pain and damage. 3, should pay attention to the appearance of prostatic fluid during massage, parallel microscopic examination. 4, in the massage should pay attention to the size and hardness of the prostate, whether the surface is smooth, with no nodules and tenderness, whether the central groove exists, becomes shallow or disappear, whether the gland is fixed, whether there is any sputum sound when it is tender, so as to achieve inspection the goal of. Inspection process Inspection method: venipuncture, blood test. Not suitable for the crowd Generally there are no special taboos. Adverse reactions and risks It generally does not cause complications and harm.