Interventional intrauterine sampling

Intrauterine sampling has certain traumatic properties, which may lead to fetal loss, amniocentesis and other complications. The fluff may also lead to fetal limb malformation. Therefore, the examination should have clear indications and be based on informed consent. Before the medical examination, the description includes past medical records, menstrual menstruation in the last 3 months, problems in menstruation, problems in sexual life, and the progress of previous pregnancy. Basic Information Specialist classification: gynecological examination classification: pathological examination Applicable gender: whether women are fasting: not fasting Tips: Before the physical examination, the description includes past medical records, menstrual periods in the last 3 months, problems in menstruation, problems in sexual life, and the progress of previous pregnancy. Normal value No Information. Clinical significance Fluff examination: The villus puncture is suitable for early pregnancy (11 weeks - 14 weeks). The best puncture point is selected according to the position of the placenta under ultrasound guidance. The placental tissue is sampled by cervical or transabdominal puncture for fetal karyotype analysis. Amniocentesis: amniocentesis is suitable for 16 weeks to 24 weeks of pregnancy. After ultrasound-guided transabdominal access to the amniotic cavity, amniotic fluid is taken for fetal karyotype analysis. Cord blood examination: Umbilical cord puncture is a diagnostic method that can be performed at any time after 20 weeks of gestation. In addition to rapid karyotype analysis, umbilical cord puncture can also be used to diagnose the infection of various intrauterine viruses and to perform intrauterine transfusion therapy on various anemias of the fetus. Fetal microscopy: Fetal microscopy is performed under the guidance of B-ultrasound with a very fine fiber endoscope (fetal mirror) from the abdominal wall of pregnant women, through the uterine wall into the amniotic cavity, observing the fetus, while also collecting cord blood and placental blood. Fetal tissue biopsy, intrauterine treatment or even biopsy of abnormal fetuses. Precautions Before the medical examination, the description includes past medical records, menstrual menstruation in the last 3 months, problems in menstruation, problems in sexual life, and the progress of previous pregnancy. Inspection process (1) Fluff examination Three ways of passing through the neck, transabdominal and transvaginal iliac crest were taken, and the official cavity was guided under ultrasound guidance, and 15-20 mg of villus tissue was aspirated for examination. (two) amniocentesis Take the supine position after emptying the bladder. Abdominal disinfection should be extended to the periphery centering on the puncture point, and the radius should be no less than 10cm. Spread a sterile hole towel. The puncture site was partially anesthetized with 0.5% lidocaine infiltration. The 7th sterile waist pierced needle was inserted vertically. Through the two resistances of the abdominal wall and the uterine wall, when entering the amniotic cavity, there is a feeling of loss of tissue suddenly disappearing. When the needle core is pulled out, amniotic fluid is discharged, and about 20 ml of amniotic fluid is extracted with a syringe, and immediately sent for inspection as needed. Then, the puncture needle was removed, the pinhole was covered with a cotton ball and gauze, and the tape was fixed after pressing for 5 minutes. (three) cord blood examination Ultrasound diagnosis of the position of the placenta, fetus and umbilical cord to determine the puncture point. Generally, the umbilical pedicle portion within 2 cm of the root of the near placenta is selected, and the relative fixation is easy to puncture. Under ultrasound guidance, a 22-gauge sterile puncture needle was used to pierce the umbilical blood vessels through the abdominal wall and the official cavity to extract fetal blood. The alkali degeneration test is used to determine the absence of maternal blood contamination for examination. (four) fetal mirror examination The fetal mirror enters the amniotic cavity through the abdominal wall, and can observe the fetal shape and body surface structure, and can carry out fetal blood collection and fetal tissue (liver, skin) biopsy for prenatal diagnosis or intrauterine blood transfusion. Not suitable for the crowd The examination should have clear indications and be based on informed consent. Adverse reactions and risks Intrauterine sampling has certain traumatic properties, which may lead to fetal loss, amniocentesis and other complications. The fluff may also lead to fetal limb malformation.