Indocyanine green retention test

The indocyanine green retention test is of great value in the evaluation of liver reserve function and liver transplantation and recipient selection. Indigo green is a dark green non-toxic pigment with minimal side effects. It is selectively ingested by liver cells after intravenous injection and is discharged into the bile in its original form. Indocyanine green does not participate in the liver and intestine circulation, and is not excreted by the kidney. After continuous blood collection, the retention rate can be determined; the main factors affecting the removal of indocyanine green are liver blood flow, total number of functional hepatocytes, bile secretion and biliary patency. Basic Information Specialist classification: Digestive examination classification: biochemical examination Applicable gender: whether men and women apply fasting: fasting Tips: This test is not suitable for patients with phthalocyanine sensitive. Normal value The cyanide green 15min retention rate is <14%, which is feasible for hepatic resection in patients with cirrhosis. Clinical significance Abnormal results: cyanocyanine 15min retention rate <14%, is feasible for hepatic resection in patients with cirrhosis, but when the cyanide green 15min retention rate is >14%, the risk of death from hepatic cirrhosis patients with hepatectomy is the former 3 times. Need to check the crowd: patients with abnormal liver reserve function. Precautions Before the test: Weighing, a certain dose of indocyanine green is given according to its weight. At the time of examination: After the injection of indocyanine green, it is necessary to wait 15 minutes for complete reaction in the body before blood can be drawn. Inspection process The blood sampling method is the traditional spectrophotometry: after the peripheral vein is cyanogen green, the blood is sampled from the other peripheral blood vessel such as the median vein of the elbow, and blood samples are taken at intervals of 3 min or 5 min, respectively, and the absorbance is measured to calculate the concentration of indocyanine green in the body. . Not suitable for the crowd Unsuitable for people: patients who are sensitive to indocyanine green. Adverse reactions and risks No related complications and hazards have been found.