Urinary β2-microglobulin clearance

Urine β2 microglobulin clearance is an auxiliary test for judging whether glomerular function is normal. 2-2-microglobulin is produced in lymphocytes and has a small amount in urine. Because of its small molecular weight, it can freely pass through the glomerulus to filter the membrane. The increase of β2-microglobulin in urine should consider whether the synthesis is increased or the reduction of proximal convoluted tubule reabsorption. If there is no disease that causes an increase in synthesis, the increase may reflect a decrease in proximal tubular reabsorption function. Acute tubular damage or necrosis, chronic interstitial nephritis and chronic renal failure can cause a significant increase in urinary β2-microglobulin. Basic Information Specialist classification: urinary examination classification: urine / kidney function test Applicable gender: whether men and women apply fasting: not fasting Tips: Check that you must not drink in the morning on an empty stomach or even water. Due to meals (especially after a meal), urine or other foreign objects are mixed in the urine. If you eat a lot of protein on the day of urine retention, or infusion of albumin will confuse the results with the actual situation, you should remind patients not to eat when checking. Normal value The normal range is 100 to 300. Clinical significance Abnormal results: The ratio increased renal tubular damage. Found in proximal tubular damage, autoimmune diseases, malignant tumors, liver disease, rejection after organ transplantation, AIDS, etc. The ratio reduces glomerular damage. Found in acute or chronic glomerulonephritis, nephrotic syndrome and so on. People who need to be examined: suspected to be dysfunctional glomeruli. Precautions Taboo before inspection: Check that you must not drink in the morning on an empty stomach or even water. Requirements for inspection: Due to meals (especially after a meal), urine or other foreign objects are mixed in the urine. If you eat a lot of protein on the day of urine retention, or infusion of albumin will confuse the results with the actual situation, you should remind patients not to eat when checking. Inspection process The doctor took the patient's urine, and the doctor took 50 ml of fresh urine in the morning, and sent the obtained urine to the laboratory for testing. After the result was obtained, the doctor informed the patient and judged the corresponding symptoms. The abnormal result was prescribed. treatment. Not suitable for the crowd Inappropriate people: Generally, there is no suitable for the crowd. Adverse reactions and risks No related complications or hazards.