Kaibocom test

The Kaibotong test is carried out by the following principle: Kaibotong is an angiotensin-converting enzyme inhibitor that inhibits the conversion of angiotensin I to II, thereby reducing the secretion of aldosterone and lowering blood pressure. Kaibotong test and examination process: overnight in the general food position, take blood in the empty stomach at 8 o'clock the next day and measure blood pressure. Immediately after taking the blood, open Botong 25mg, continue to recumbent for 2 hours, at 10:00 am Blood samples were taken for plasma aldosterone, renin activity and angiotensin II concentration and blood pressure was measured [Results] After taking captopril, blood aldosterone was not inhibited to below 416 pmol/L, suggesting that aldosterone secretion is not affected by renin. Angiotensin regulation, thus supporting the diagnosis of primary aldosterone. Basic Information Specialist classification: cardiovascular examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Tips: You should pay attention to the normal diet before the examination, pay attention to normal work and rest, and prevent endocrine disorders. Normal value Aldosterone levels were normal. In normal or patients with essential hypertension, plasma aldosterone levels were inhibited to below 416 pmol/L (15 mg/dl) after taking captopril. Clinical significance In normal or patients with essential hypertension, plasma aldosterone levels were inhibited to below 416 pmol/L (15 mg/dl) after captopril, whereas plasma aldosterone was not inhibited in patients with primary aldosteronism. Primary aldosteronism, also known as aldosteronism. Abnormal results There are three types of clinical symptoms of aldosteronism: 1. Hypertensive patients have high blood pressure, and appear earlier, often appear in about 4 years before the onset of hypokalemia. Generally, it is moderately elevated, and the increase in diastolic blood pressure is more obvious. 2. Neuromuscular dysfunction: (1) Neuromuscular weakness and paralysis Generally speaking, the lower the blood potassium, the heavier the myopathy. Tiredness, coldness, tension, diarrhea, sweating, and loss of potassium-diuretic diuretics (such as hydrochlorothiazide, furosemide) can be induced. It is often found that the lower limbs cannot move autonomously when they wake up in the morning. The severity of the attack varies, and the severe one can affect the upper limbs, sometimes involving the respiratory muscles. Cranial nerve innervation muscles are generally unaffected. Bilateral flaccid convulsions at the time of onset. (2) Paroxysmal hand, foot and ankle and muscle spasm were found in about 1/3 of patients, with beam arm compression sign (Trousseau sign) and facial nerve attack sign (Chvostek sign). It can last for days to weeks. Can appear alternately with paroxysmal paralysis. 3. Loss of potassium nephropathy and pyelonephritis. People who need to be examined: patients with hypertension, neuromuscular dysfunction, potassium-deficient nephropathy and pyelonephritis. Or want to judge by this test is a patient with essential hypertension or hypertensive patients with hypertension caused by aldosteronism. Precautions Forbidden before examination: pay attention to normal diet, pay attention to normal work and rest, and prevent endocrine disorders. Requirements for inspection: Actively cooperate with the doctor's request. Inspection process [method] In the supine food overnight, the blood was taken from the empty stomach at 8 o'clock the next day and blood pressure was measured. Immediately after the blood was taken, 25 mg of Bobotong was administered orally, and the patient was kept in a lying position for 2 hours. Blood was taken at 10:00 am in the morning to measure plasma aldosterone and kidney. Activity and angiotensin II concentration and blood pressure. [Result analysis] After taking captopril, the blood aldosterone was not inhibited to below 416 pmol/L, suggesting that the secretion of aldosterone is not regulated by renin-angiotensin, thus supporting the diagnosis of primary aldosterone. Not suitable for the crowd Inappropriate crowd: temporarily unknown. Adverse reactions and risks No related complications or hazards.