Determination of renin activity in lateral renal veins

The lateral renal venous renin activity assay is a measure of the ratio of renal venous renin activity on both sides (affected renin/contralateral renin, RVRR) and peripheral circulating renin or contralateral renal vein renin and surrounding The ratio of blood to renin. It is generally believed that the peripheral blood renin activity is high and the difference in renal venous renin activity is greater than 2 times, the surgical effect is good, Kaufman reported an effective rate of 93%. Abdominal main renal angiography is an examination to check whether the kidney has cancer. It is an important means for early diagnosis and qualitative diagnosis of renal tumors. Basic Information Specialist classification: urinary examination classification: urine / kidney function test Applicable gender: whether men and women apply fasting: fasting Tips: You should keep your routine and diet regular before you check. Normal value The peripheral blood renin activity was normal or the ratio of contralateral renal vein to peripheral blood renin was less than 1.3. Clinical significance Abnormal results: the peripheral blood renin activity was normal or the ratio of contralateral renal vein to peripheral blood renin was less than 1.3, and the difference in renal venous renin activity between the two sides was greater than 1.4 times, the postoperative blood pressure returned to normal or significantly decreased; If the ratio of renin activity on both sides is less than 1.4, the surgical effect is not good. The false positive rate is about 7%. Vaughan (1985) also believes that 90% of renal vascular hypertension can achieve good surgical results when the renal venous renin ratio is 1.5:1, but the negative ratio does not rule out satisfactory response after surgery. The false negative rate is about 15%. (62/412). On the other hand, positive RVRR can not rule out bilateral lesions, and correcting one side of the lesion can not completely correct the basic pathological changes, so hypertension can not be effectively controlled. People who need to be examined: suspected of abnormal kidney function. Precautions Taboo before the examination: the routine should be kept normal and the diet should be regular before the examination. Requirements for examination: 1 application of renin sodium index, that is, stimulation with captopril showed high secretion of renin; 2 confirmed contralateral no renin secretion, V2-A2 = 0 (representing renal vein and Renal artery renin value); 3 in unilateral high renin-type renal vascular hypertension V-IVCV/IVC ≥ 0.5 (IVC refers to inferior vena cava renin value), while essential hypertension is different, regardless of its surroundings Whether the renin is normal or elevated, both sides of V-IVC/IVC are equal to 0.25. Inspection process The blood column obtained by mistakenly inserting the catheter into other branches or at the proximal end of the renal vein includes reflux of other veins, causing the plasma intravenous renin in the renal vein to be diluted and illusory. The use of a single catheter to collect two renal veins for renin activity determination often results in errors, so it is recommended to use three catheters to simultaneously collect three renal vein specimens. If two of the renin activity values ​​are similar, it is considered reliable, and the positive rate is more than 90% in the case of unilateral renal artery stenosis hypertension. Not suitable for the crowd Inappropriate people: Generally, there is no suitable for the crowd. Adverse reactions and risks No related complications or hazards.