carbon dioxide binding force

Carbon dioxide binding is the amount of carbon dioxide dissolved in plasma or serum at a specific temperature and pressure, that is, the patient's plasma is equilibrated with normal human alveolar gas (pCO2 is 5.32 kPa) under air-insulated conditions. The measured plasma CO2 content, minus the value of the known CO2 fraction dissolved in plasma, reflects the amount of alkali storage in the body, mainly used to understand the content of sodium bicarbonate in the blood, to determine whether there is acid-base balance Disorder and its extent, determine the function of the kidney to regulate acid-base balance. Basic Information Specialist classification: Respiratory examination classification: pulmonary function test Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Reduced: seen in metabolic acidosis. Normal value: Adult: 22-29mmol/L Children: 18-27mmol/L Above normal: Increased: seen in respiratory acidosis. negative: Positive: Tips: Patients take venous blood for examination according to the doctor's request. Normal value Adult 22 ~ 31mmol / L; Children 18 ~ 27mmol / L; Microtiter method 23 ~ 30mmol / L. Clinical significance Abnormal results: (1) Increased metabolic alkalosis (such as caused by acute gastritis, pyloric obstruction, pregnancy vomiting, adrenal hyperfunction, hypokalemia, excessive use of basic drugs, excessive use of dexamethasone), or generation Respiratory acidosis after remission (eg caused by chronic bronchitis, obstructive emphysema, pulmonary heart disease, bronchial asthma status, bronchiectasis, extensive pulmonary fibrosis, lung consolidation, morphine poisoning, etc.). Common in pyloric obstruction, severe vomiting, excessive loss of gastric acid; or metabolic alkalosis caused by excessive alkaline drugs, and pulmonary heart disease such as pulmonary heart disease caused by compensatory respiratory acidosis. (2) To reduce the lack of alkali storage, for metabolic acidosis, or for compensatory respiratory alkalosis. Only metabolic acidosis, or respiratory alkalosis, shows a decrease. The reduction of carbon dioxide binding is most common in septic shock, epidemic hemorrhagic fever and other diseases. The more the reduction, the more severe the condition and the poor prognosis. Hemorrhagic fever, oliguria, and reduction in diabetic coma were more significant. It is also common in metabolic acidosis caused by severe diarrhea, renal failure, intestinal fistula and other diseases, respiratory center excitability caused by various causes, respiratory alkalosis such as various respiratory diseases. In addition, taking excessive amounts of acidic drugs (such as sodium salicylate) can also reduce the binding force of carbon dioxide. The severity of metabolic acidosis is divided according to the degree of reduction of carbon dioxide binding capacity. Mild acidosis 22.45～17.96mmol/L Moderate acidosis 17.96~13.47mmol/L Severe acidosis <13.47mmol/L The prognosis is extremely serious <6.74mmol/L Acid-base balance imbalance can not be completely confirmed by acid poisoning or alkalosis. Blood acidity and alkalinity should be measured simultaneously in respiratory acidosis and alkalosis. In addition to the influence of primary respiratory factors, the increase or decrease of the value can indicate the increase or decrease of the amount of bicarbonate to reflect the degree of metabolic acid-base balance disorder. Need to check the crowd: patients with difficulty breathing, changes in body fluid pH, decreased resistance and other patients. Precautions Requirements for examination: The patient takes venous blood for examination according to the doctor's request. Venous blood should be preserved in an anaerobic environment. The patient's plasma is equilibrated with the normal human alveolar gas. Inspection process The venous blood of the patient is taken by using a clean test tube on an empty stomach, and the blood sample is centrifuged to separate into a plasma component and a blood cell component, and the upper layer is taken overnight, and under the condition of air isolation, the alveolar gas is balanced with a normal person, and then the carbon dioxide is detected by titration. Specific content. Not suitable for the crowd Inappropriate people: Generally, there is no suitable for the crowd. Adverse reactions and risks No related complications or hazards.