CSF oligoclonal electrophoresis analysis

The determination of CSF-restricted OCB (CSF-OCB) can qualitatively reflect the clinical significance of intrathecal immunoglobulin synthesis and cerebrospinal fluid oligoclonal zone (CSF-OCB) in neurological disorders. Basic Information Specialist classification: neurological examination classification: cerebrospinal fluid examination Applicable gender: whether men and women apply fasting: not fasting Analysis results: Below normal: Normal value: no Above normal: negative: normal. Positive: The cerebrospinal fluid oligoclonal zone is positive and may be a nervous system inflammatory or non-inflammatory disease, multiple sclerosis disease. Reminder: those with elevated intracranial pressure, purulent infections in the perforating area, open cranial injury or cerebrospinal fluid leakage are not suitable for this examination. Normal value The cerebrospinal fluid oligoclonal zone was negative. Clinical significance Abnormal results: The cerebrospinal fluid oligoclonal zone is positive and may be a nervous system inflammatory or non-inflammatory disease, multiple sclerosis disease. Need to check the crowd: nervous system diseases, multiple sclerosis patients. Precautions Pre-inspection contraindications: Prevent head damage on the day before the test. Requirements for examination: Actively cooperate with doctors, spinal compression should be cautious when doing lumbar puncture, because lumbar puncture can increase the symptoms of spinal cord compression, prolong prothrombin time, platelet count less than 50X109 / L, use heparin or any cause of bleeding The tendency should be worn after the coagulation disorder is corrected. Inspection process A small amount of cerebrospinal fluid was assent in the patient's brain, and the clonal zone in the cerebrospinal fluid was monitored by iso-focus electrophoresis. Not suitable for the crowd Inappropriate population: those with elevated intracranial pressure, purulent infections in the perforating area, open head injury or cerebrospinal fluid leakage. Adverse reactions and risks No obvious complications and harms.