Chemical examination of cerebrospinal fluid

The chemical examination of cerebrospinal fluid mainly checks protein, chloride, glucose, pH, and provides a basis for diagnosing diseases. Basic Information Specialist classification: neurological examination classification: cerebrospinal fluid examination Applicable gender: whether men and women apply fasting: not fasting Tips: Actively cooperate with the doctor's request. Normal value 1. Protein quantification: lumbar puncture 0.15-0.45g/L; ventricle puncture 0.05-0.15g/L; brain pool puncture 0.10-0.25g/L. 2, protein electrophoresis: prealbumin 0.03-0.07; albumin 0.51-0.63; 1-1-globulin 0.06-0.08; α2-globulin 0.06-0.10; --globulin 0.14-0.19; γ-globulin 0.06-0.10. 3. Quantitative glucose: 2.8-4.5 mmol/L for adults; 3.1-4.4 mmol/1 for children; 3.9-5.0 mmol/L for infants. 4. Determination of chloride: 120-132 mmol/L; 111-123 mmol/L for children; 110-122 mmol/L for infants. Clinical significance Abnormal results: 1. Purulent meningitis, the protein content of epidemic meningitis is 3-6.5g/L; the protein content of tuberculous meningitis stimulates symptom period is 0.3-2.0g/L, the period of compression symptoms is 1.9-7g/L, paralysis period It is 0.5-6.5 g/L; the encephalitis protein content is 0.5-3.0 g/L. 2. Diseases that cause cerebrospinal fluid circulation obstruction, such as spinal arachnoiditis and spinal cord tumors, the protein content of which can be above 1.0g / L. 3. Brain softening, tumor, degenerative diseases, etc., cerebrospinal fluid protein can be increased to 0.25-0.8g / L. 4. Cerebrospinal fluid protein such as multiple radiculitis, serous meningitis, cerebral spinal cord syphilis, paralytic dementia, cerebral hemorrhage, cerebral embolism, subarachnoid hemorrhage, epidemic encephalitis, polio, etc. 5. Prealbumin increased chorea, Parkinson's disease, acromegaly; prealbumin reduction is meningitis. 6. Albumin increases cerebrovascular disease, such as cerebral infarction, cerebral hemorrhage, etc.; albumin is reduced to acute phase of brain trauma. 7. α1-globulin increases meningitis, poliomyelitis and the like. 8. α2-globulin increases brain tumors, metastatic cancer, glioma and the like. 9. β-globulin increased some degenerative changes such as Parkinson's disease, hemiplegia after trauma. 10. γ-globulin increases glioma, severe brain trauma, epilepsy, optic neuromyelitis, multiple sclerosis, brain infection, peripheral neuritis, etc. 11. Cerebrospinal fluid glucose increases blood cerebrospinal fluid, diabetes, brain stem acute trauma or poisoning, premature infants or newborns. 12. Cerebrospinal fluid glucose reduces acute suppurative meningitis, tuberculous meningitis, fungal meningitis, neurosyphilis, brain tumors. 13. Cerebrospinal fluid chloride increased chronic renal insufficiency, nephritis, uremia, serous meningitis. 14. Cerebrospinal fluid chloride reduces epidemic meningitis, purulent meningitis and other fine meningitis. Precautions Pre-inspection requirements: None. Requirements for inspection: Actively cooperate with the doctor's request. Inspection process The physician takes a small amount of cerebrospinal fluid from the patient's brain and performs protein, chloride, and glucose monitoring. Not suitable for the crowd Not suitable for the crowd: no. Adverse reactions and risks No obvious complications and harms.

Was this article helpful?

The material in this site is intended to be of general informational use and is not intended to constitute medical advice, probable diagnosis, or recommended treatments.